Introduction：Basic information about Ethyl nicotinate CAS 614-18-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Ethyl nicotinate Basic information
| Product Name: | Ethyl nicotinate |
| Synonyms: | RARECHEM AL BI 0185;NICOTINIC ACID ETHYL ESTER;ETHYL 3-PYRIDINECARBOXYLATE;ETHYL PYRIDINE-3-CARBOXYLATE;2,4-dimethoxy-N-[(E)-2-(1,3,3-trimethyl-2-indol-1-iumyl)ethenyl]aniline;Ethyl nicotinate,99%,stabilized;2-ethylpyridine-3-carboxylic acid;Ethyl Nicontinate |
| CAS: | 614-18-6 |
| MF: | C8H9NO2 |
| MW: | 151.16 |
| EINECS: | 210-370-7 |
| Product Categories: | Organic acids;Heterocyclic Compounds;CARBOXYLICESTER;Building Blocks;C8 to C9;Chemical Synthesis;Aromatics;Heterocycles;Nicotine Derivatives;Heterocyclic Building Blocks;Pyridines;614-18-6;bc0001 |
| Mol File: | 614-18-6.mol |
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Ethyl nicotinate Chemical Properties
| Melting point | 8-10 °C (lit.) |
| Boiling point | 223-224 °C (lit.) |
| density | 1.107 g/mL at 25 °C (lit.) |
| vapor pressure | 4.2-5.5Pa at 20-25℃ |
| refractive index | n20/D 1.504(lit.) |
| Fp | 93 °C |
| storage temp. | Store below +30°C. |
| solubility | 50g/l |
| form | liquid |
| pka | pK1:3.35(+1) (25°C) |
| color | light yellow |
| Specific Gravity | 1.107 |
| Water Solubility | miscible |
| BRN | 122937 |
| Cosmetics Ingredients Functions | SKIN CONDITIONING
PERFUMING |
| InChI | 1S/C8H9NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h3-6H,2H2,1H3 |
| InChIKey | XBLVHTDFJBKJLG-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1cccnc1 |
| LogP | 1.32 |
| Surface tension | 72mN/m at 1g/L and 20℃ |
| CAS DataBase Reference | 614-18-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Pyridinecarboxylic acid, ethyl ester(614-18-6) |
| EPA Substance Registry System | Ethyl nicotinate (614-18-6) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 37/38-41-36/38-36/37/38 |
| Safety Statements | 26-39-37/39-36 |
| WGK Germany | 3 |
| F | 8-9-23 |
| TSCA | TSCA listed |
| HS Code | 29333999 |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| Hazard Classifications | Eye Dam. 1
Skin Corr. 1B
STOT SE 3 |
| Toxicity | LD50 orally in Rabbit: > 2005 mg/kg |
Ethyl nicotinate Usage And Synthesis
| Description | Ethyl nicotinate is a chemical attractant used to prevent and control plant pests. Ethyl nicotinate was found to be a potent attractant forThrips obscuratus in peaches and apricots. It is more attractive than ripe fruit and catches peak at harvest. Long season trapping demonstrated the efficiency of chemical traps compared to unbaited traps. The attractiveness of the chemical was maintained for at least 2 weeks when 50 μl of the chemical was placed in an open 2 ml vial cap. Various pyralids, geometrids (Lepidoptera), and chironomids (Diptera) were also attracted in low numbers to ethyl nicotinate[1]. |
| Chemical Properties | clear colourless to yellow liquid |
| Uses | Ethyl nicotinate is a nicotinic acid derivative used for skin-conditioning cosmetics. |
| Uses | Ethyl nicotinate is used for skin-conditioning cosmetics. It is principally used in medicine as a local vasodilator at a concentration of 1 to 2 % in creams, ointments and pomades. It is utilized for the treatment sprains, wrenches, muscular pains and tendonitis. |
| Definition | ChEBI: Ethyl nicotinate is a member of pyridines and an aromatic carboxylic acid. |
| Solubility in water | Soluble in water (50 mg/ml at 20° C). |
| References | [1] D R PENMAN. Ethyl nicotinate?: A chemical attractant forThrips obscuratus (Thysanoptera: Thripidae) in stonefruit in New Zealand.[J]. Journal of Chemical Ecology, 1982. DOI:10.1007/BF00987763. |
Ethyl nicotinate Preparation Products And Raw materials
| Preparation Products | Imazethapyr-->2-cyano-2-[2,3-dihydro-3-(tetrahydro-2,4,6-trioxo-5(2H)-pyrimidinylidene)-1H-isoindol-1-ylidene]-N-methylacetamide-->4-(3-AMINOPROPYL)-2,4-DIHYDRO-3H-PYRAZOL-3-ONE-->2-AMINO-3-PYRIDINECARBOXALDEHYDE HCL-->Ethyl 1,4,5,6-tetrahydropyridine-3-carboxylate-->Ethyl (3R)-piperidine-3-carboxylate-->ETHYL NIPECOTATE-->(+/-)-NICOTINE-->Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate-->3-Pyridylmethyl-N-(p-nitrophen-->3-(3-Phenylpropyl)piperidine |
