Hydrazine monohydrochloride CAS 2644-70-4

Introduction：Basic information about Hydrazine monohydrochloride CAS 2644-70-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Hydrazine monohydrochloride Basic information

• Product Name: Hydrazine monohydrochloride
• Synonyms: HYDRAZINE MONO HCL;HYDRAZINE MONOHYDROCHLORIDE;HYDRAZINIUM MONOCHLORIDE;HydrazineHCl;Hydrazine hydrochloride, mono-;Hydrazine monohydrochloride, 98+%;Hydrazinium chloride;Hydrazine hydrochloride: (Hydrazine monochloride)
• CAS: 2644-70-4
• MF: ClH5N2
• MW: 68.51
• EINECS: 220-154-4
• Product Categories: Reduction;Synthetic Organic Chemistry;Pharmaceutical Intermediates;Hydrazines;Nitrogen Compounds;Organic Building Blocks
• Mol File: 2644-70-4.mol

Hydrazine monohydrochloride Chemical Properties

• Melting point: 89 °C(lit.)
• Boiling point: 240°C
• density: 1.500
• storage temp.: Inert atmosphere,Room Temperature
• solubility: DMSO (Slightly), Methanol (Slightly)
• form: white orthorhombic crystals
• color: White to Almost white
• Water Solubility: 370 g/L (20 ºC)
• Stability: Hygroscopic
• InChI: InChI=1S/ClH.H4N2/c;1-2/h1H;1-2H2
• InChIKey: BIVUUOPIAYRCAP-UHFFFAOYSA-N
• SMILES: NN.Cl
• CAS DataBase Reference: 2644-70-4(CAS DataBase Reference)
• EPA Substance Registry System: Hydrazine, monohydrochloride (2644-70-4)

Safety Information

• Hazard Codes: T,N
• Risk Statements: 45-23/24/25-43-50/53
• Safety Statements: 53-45-60-61
• RIDADR: UN 2923 8/PG 2
• WGK Germany: 3
• RTECS: MV4625000
• TSCA: TSCA listed
• HazardClass: 6.1(a)
• PackingGroup: II
• HS Code: 28251090
• Storage Class: 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Aquatic Acute 1 Aquatic Chronic 1 Carc. 1B Skin Sens. 1

Hydrazine monohydrochloride Usage And Synthesis

Chemical Properties

Hydrazine monohydrochloride is white to slightly beige crystals or cryst. powder; melts at 93°C; decomposes around 200°C; very soluble in water (37 g/100mL at 20°C); slightly soluble in alcohol.

Physical properties

White flakes; orthorhombic crystals; density 1.5 g/cm³; melts at 93°C;decomposes around 200°C; very soluble in water (37 g/100mL at 20°C); slightly soluble in alcohol.

Uses

Hydrazine monohydrochloride has been used:

• as catalyst in the synthesis of titanium oxide polymers via catalytic sol-gel process
• in fabrication of amorphous titanium dioxide (TiO₂) thin films exhibiting high refractive indices and high transparency
• in preparation of ethyl 3-ethoxy-1H-pyrazole-4-carboxylate

Uses

Hydrazine hydrochloride is used to prepare other hydrazine derivatives.

Preparation

Hydrazine hydrochloride is prepared by the reaction of hydrazine with hydrogen chloride:
N2H4 + HCl → N2H4 •HCl

Hazard

Hydrazine hydrochloride is moderately toxic by all routes of exposure. Theoral LD50in mice is 126 mg/kg.

Purification Methods

Prepare it by dropwise addition of cold conc HCl to cold liquid hydrazine in equimolar amounts. The crystals are harvested from water and are twice recrystallised from absolute MeOH and dried under a vacuum. [Kovack et al. J Am Chem Soc 107 7360 1985.]

Toxicity evaluation

Hydrazine hydrochloride is moderately toxic by all routes of exposure. The oral LD50 in mice is 126 mg/kg.

Hydrazine monohydrochloride Preparation Products And Raw materials

• Preparation Products: Pyridaben-->3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBONITRILE-->3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBOXAMIDE-->3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE-->(3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANAMINE-->(3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL-->3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-AMINE-->ETHYL 3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLATE-->3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID-->3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-5-CARBOXYLIC ACID-->4-BROMO-3-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-->2-(3-BROMOPHENYL)-5-(2-NAPHTHYL)-1,3,4-OXADIAZOLE-->2-(4-BROMOPHENYL)-5-(1-NAPHTHYL)-1,3,4-OXADIAZOLE-->1-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOLE-->2-(4-tert-Butylphenyl)-5-(4-biphenyl)-1,3,4-oxadiazole-->Carboplatin-->2,5-DIPHENYL-1,3,4-OXADIAZOLE-->2,5-BIS(1-NAPHTHYL)-1,3,4-OXADIAZOLE-->2,5-BIS(3-NITROPHENYL)-1,3,4-OXADIAZOLE-->2,5-BIS(3-METHOXYPHENYL)-1,3,4-OXADIAZOLE-->2,5-BIS(4-BIPHENYLYL)-1,3,4-OXADIAZOLE-->2-NAPHTHHYDRAZIDE-->4-tert-Butylbenzhydrazide-->Ethyl 3-methyl-1H-pyrazole-5-carboxylate-->3-(Trifluoromethyl)pyrazole