| Chemical Properties | Isobutylamine is a flammable liquid, miscible with water, alcohol, andether. Colorless to yellow liquid; fishy cheesy aroma.
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| Uses | Isobutylamine may be used in the synthesis of N-i-butyl-9(Z),12(Z),15(Z)-octadecatrienamide by reacting with trilinolenin. It can also react with tropolone to form a hydrogen-bonded complex, iso-butyl-ammonium 7-oxo-cyclo-hepta-1,3,5-trien-1-olate. Fullerene (C60) can undergo oxyamination with isobutylamine to form polyamines. |
| Production Methods | Isobutylamine is manufactured from isobutanol and ammoniaor by the thermal decomposition of valine to isoleucine. |
| Aroma threshold values | High strength odor, fishy type; recommend smelling in a 0.10% solution or less. |
| General Description | Isobutylamine is a clear colorless liquid with a fishlike odor. Flash point 15°F. Less dense (6.1 lb / gal) than water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. |
| Reactivity Profile | Isobutylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. |
| Health Hazard | Inhalation causes severe coughing and chest pain due to irritation of air passages; can cause lung edema. Compound is sympathomimetic and is also a cardiac depressant and convulsant; ingestion causes nausea and profuse salivation. Contact with eyes causes severe irritation and edema of the cornea. Contact with skin causes severe irritation. |
| Chemical Reactivity | Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent. |
| Potential Exposure | Isobutylamine: Possible risk offorming tumors, suspected of causing genetic defects, suspected reprotoxic hazard, Primary irritant (w/o allergicreaction), (sec-isomer): Drug. n-Butylamine is used inpharmaceuticals; dyestuffs, rubber, chemicals, emulsifyingagents; photography, desizing agents for textiles; pesticides, and synthetic agents. sec-Butylamine is used as afungistate. tert-Butylamine is used as a chemical intermediate in the production of tert-Butylaminoethyl methacrylate(a lube oil additive); as an intermediate in the productionof rubber and in rust preventatives and emulsion deterrentsin petroleum products. It is used in the manufacture ofseveral drugs. |
| Shipping | UN1125 n-Butylamine, Hazard Class: 3; Labels:3—Flammable liquid, 8—Corrosive material. UN2014Isobutylamine, Hazard Class: 3; Labels: 3—Flammableliquid, 8—Corrosive material |
| Incompatibilities | May form explosive mixture with air.May accumulate static electrical charges, and may causeignition of its vapors. n-Butylamine is a weak base; reactswith strong oxidizers and acids, causing fire and explosionhazard. Incompatible with organic anhydrides; isocyanates,vinyl acetate; acrylates, substituted allyls; alkylene oxides;epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks some metals inpresence of moisture. The tert-isomer will attack someforms of plastics |
| Waste Disposal | Use a licensed professionalwaste disposal service to dispose of this material. Dissolveor mix the material with a combustible solvent and burn ina chemical incinerator equipped with an afterburner andscrubber. All federal, state, and local environmental regulations must be observed. |
