Lanolin CAS 8006-54-0
Introduction：Basic information about Lanolin CAS 8006-54-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Lanolin Basic informationDescription Benefits
| Product Name: | Lanolin |
| Synonyms: | WOOL FAT;ADEPS LANAE;BASE, LANOLIN OINTMENT, HYDRATED, HYDROPHILIC;BASE, LANOLIN OIL AND CARBAMIDE OINTMENT, HYDRATED, HYDROPHILIC;HYPOALLERGENIC LANOLIN;LANOLIN DEHYDRATE;LANOLIN OIL;LANOLIN HYDROUS |
| CAS: | 8006-54-0 |
| MF: | N/A |
| MW: | 0 |
| EINECS: | 232-348-6 |
| Product Categories: | Steroids;Cosmetics;8006-54-0 |
| Mol File: | Mol File |
Lanolin Chemical Properties
| Melting point | 38-40 °C |
| density | 0.932-0.945 g/cm3(Temp: 15 °C) |
| Fp | 209 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | chloroform: 0.1 g/mL, clear to faintly turbid (<29 NTU), strongly yellow-green |
| form | Adhering Crystals or Powder |
| color | White to yellow |
| Odor | Characteristic |
| Water Solubility | Soluble in ether, petroleum ether, chloroform and petroleum benzene. Sparingly soluble in ethanol. Insoluble in water. |
| Merck | 14,5358 |
| Dielectric constant | 4.2（Ambient） |
| Cosmetics Ingredients Functions | HAIR CONDITIONING ANTISTATIC SURFACTANT - EMULSIFYING SURFACTANT - CLEANSING SKIN CONDITIONING SKIN CONDITIONING - EMOLLIENT |
| Cosmetic Ingredient Review (CIR) | Lanolin (8006-54-0) |
| EPA Substance Registry System | Lanolin (8006-54-0) |
Safety Information
| Safety Statements | 24/25 |
| WGK Germany | 1 |
| RTECS | OE3201000 |
| Autoignition Temperature | 833 °F |
| TSCA | TSCA listed |
| HS Code | 15050000 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 8006-54-0(Hazardous Substances Data) |
| Description | Lanolin oil is a secretion from sheep’s skin. It’s similar to human sebum, an oil secreted by the sebaceous glands that you may notice particularly on your nose.Unlike sebum, lanolin contains no triglycerides. Lanolin is sometimes referred to as “wool fat,” but the term is misleading because it lacks triglycerides needed to be considered a fat.The purpose of lanolin is to condition and protect sheep’s wool. This conditioning property is why the substance is now widely used in human cosmetics, skin care, and hair products.Lanolin oil is extracted by putting sheep’s wool through a centrifuge machine that separates the oil from other chemicals and debris. The process is performed after the sheep is sheared so the extraction of lanolin causes no harm to sheep. |
| Benefits | Lanolin is a very good ingredient for someone with dry skin, though it can be a problem for someone with oily or breakout-prone skin. Also, as an animal-derived ingredient, lanolin is sometimes viewed as less favorable in comparison to synthetic or plant-derived alternatives. |
| Chemical Properties | yellow wax |
| Chemical Properties | Lanolin is a pale yellow-colored, unctuous, waxy substance with afaint, characteristic odor. Melted lanolin is a clear or almost clear,yellow liquid. |
| Characteristics | Lanolin is a waxy substance that sheep naturally produce to protect their wool. Because lanolin's properties are similar to those of the sebum (oil) secreted by human skin, it is a popular ingredient in moisturizers, hair care products, and soaps. |
| Uses | lanolin (hydrogenated) is a lanolin derivative. |
| Uses | lanolin is an emollient with moisturizing properties and an emulsifier with high water–absorption capabilities. It forms a network on the skin’s surface rather than a film, as is the case with petrolatum (Vaseline.). While long-term studies associate a low incidence of allergic reactions to lanolin, it remains a controversial ingredient based on a potential pesticide content and potential comedogenicity. There is a move among high-quality lanolin manufacturers to produce low-pesticide lanolin and among high-quality cosmetic formulators and manufacturers to use the purist form available. Lanolin’s comedogenicity potential is increasingly debated as some researchers believe it to be inaccurate, especially when lanolin is used in an emulsion. Lanolin is a sheep’s wool derivative formed by a fat-like viscous secretion of the sheep’s sebaceous glands. Some consider it a natural wax. |
| Uses | lanolin wax is a lanolin derivative. This is the semisolid fraction of lanolin obtained by physical means from whole lanolin. |
| Production Methods | Lanolin is a naturally occurring wax-like material obtained fromthe wool of sheep, Ovis aries Linne′ (Fam. Bovidae). Crude lanolin is saponified with a weak alkali and the resultantsaponified fat emulsion is centrifuged to remove the aqueous phase.The aqueous phase contains a soap solution from which, onstanding, a layer of partially purified lanolin separates. Thismaterial is then further refined by treatment with calcium chloride,followed by fusion with unslaked lime to dehydrate the lanolin. Thelanolin is finally extracted with acetone and the solvent is removedby distillation. |
| Definition | A yellowish viscoussubstance obtained from wool fat. It containscholesterol and terpene compounds,and is used in cosmetics, in ointments, andin treating leather. |
| Definition | lanolin: An emulsion of purified wool fat in water, containing cholesteroland certain terpene alcoholsand esters. It is used in cosmetics. |
| Pharmaceutical Applications | Lanolin is widely used in topical pharmaceutical formulations andcosmetics. Lanolin may be used as a hydrophobic vehicle and in thepreparation of water-in-oil creams and ointments. When mixedwith suitable vegetable oils or with soft paraffin, it producesemollient creams that penetrate the skin and hence facilitate theabsorption of drugs. Lanolin mixes with about twice its own weightof water, without separation, to produce stable emulsions that donot readily become rancid on storage. |
| Side effects | Most emollients can be used safely and effectively without side effects. However, burning, stinging, redness or irritation may occur. Rare and very serious allergic reactions are abnormal changes in the skin (e.g., whitening/softening/wetness from over-moisturisation), rashes, itching/swelling (especially on the face/tongue/throat), severe dizziness, and difficulty breathing. If any discomfort occurs, contact your doctor immediately. |
| Safety | Lanolin is widely used in cosmetics and a variety of topical pharmaceutical formulations. Although generally regarded as a nontoxic and nonirritantmaterial, lanolin and lanolin derivatives are associated with skinhypersensitivity reactions, and the use of lanolin in subjects withknown sensitivity should be avoided. Other reports suggest that‘sensitivity’ arises from false positives in patch testing.However,skin hypersensitivity is relatively uncommon; the incidence ofhypersensitivity to lanolin in the general population is estimated tobe around 5 per million. Sensitivity is thought to be associated with the content of freefatty alcohols present in lanolin products rather than the totalalcohol content.The safety of pesticide residues in lanolinproducts has also been of concern. However, highly refined‘hypoallergenic’ grades of lanolin and grades with low pesticideresidues are commercially available. |
| storage | Lanolin may gradually undergo autoxidation during storage. Toinhibit this process, the inclusion of butylated hydroxytoluene ispermitted as an antioxidant. Exposure to excessive or prolongedheating may cause anhydrous lanolin to darken in color anddevelop a strong rancidlike odor. However, lanolin may be sterilizedby dry heat at 150°C. Ophthalmic ointments containing lanolinmay be sterilized by filtration or by exposure to gamma irradiation. |
| Incompatibilities | Lanolin may contain prooxidants, which may affect the stability ofcertain active drugs. |
| Regulatory Status | Included in the FDA Inactive Ingredients Database (ophthalmic,otic, topical, and vaginal preparations). Included in nonparenteralmedicines licensed in the UK. Included in the Canadian List ofAcceptable Non-medicinal Ingredients. |
Lanolin Preparation Products And Raw materials
| Raw materials | FUMING SULFURIC ACID-->Water-->Benzonitrile-->laundry soap |
