Methoxyphenamine CAS 93-30-1

Introduction：Basic information about Methoxyphenamine CAS 93-30-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Methoxyphenamine Basic information

• Product Name: Methoxyphenamine
• Synonyms: Methoxyphenamine (base and/or unspecified salts);2-Methoxy-N,α-dimethylbenzeneethanamine;o-Methoxy-N,α-dimethylbenzeneethan-1-amine;o-Methoxy-N,α-dimethylbenzeneethanamine;o-Methoxy-α,N-dimethylbenzeneethanamine;2-Methoxyphenamine base;1-(2-Methoxyphenyl)-2-methylaminopropane;2-Methoxymethamphetamine
• CAS: 93-30-1
• MF: C11H17NO
• MW: 179.25878
• EINECS: 202-237-7
• Mol File: 93-30-1.mol

Methoxyphenamine Chemical Properties

• Melting point: 271℃
• Boiling point: 252℃
• density: 0.951
• Fp: 103℃
• pka: 10.36±0.10(Predicted)

Methoxyphenamine Usage And Synthesis

Chemical Properties

Oily liquid. Boiling point 97-99 ℃ (0.267kPa). Its hydrochloride is a white crystalline powder with a melting point of 129-131 °C. Soluble in water, ethanol, chloroform, slightly soluble in benzene and ether. Odorless, bitter taste. The pH of a 5% aqueous solution is 5.3-5.7.

Uses

Methoxyphenamine is an adrenaline-mimetic drug with significant bronchodilation and smooth muscle relaxation effects. It also has a mild antihistamine effect, a sedative effect and suppresses the cough center. It is suitable for treating bronchial asthma, especially for patients who cannot tolerate ephedrine.

Definition

ChEBI: Methoxyphenamine is an amphetamine methylated on nitrogen and with the phenyl ring methoxylated at C-2. A beta-adrenergic receptor agonist, it is used as a bronchodilator. It has a role as a beta-adrenergic agonist and a bronchodilator agent.

Synthesis

Methoxyphenamine is obtained by methylation and reduction of o-methoxypropiophenone.

Methoxyphenamine Preparation Products And Raw materials

• Raw materials: Methylamine-->Phenylacetone-->D/L-AMPHETAMINE HYDROCHLORIDE-->2-Methoxyphenylacetone