N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine CAS 2305415-83-0

Introduction：Basic information about N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine CAS 2305415-83-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine Basic information

• Product Name: N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine
• Synonyms: N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine;Propanamide, N-[6-(2-cyanoethoxy)-9-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-9H-purin-2-yl]-2-methyl-;N2-Isobutyryl-O6-cyanoethyl-7’-OH-N-trityl-morpholinoguanine
• CAS: 2305415-83-0
• MF: C36H37N7O4
• MW: 631.72
• Mol File: 2305415-83-0.mol

N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine Chemical Properties

• density: 1.29±0.1 g/cm3(Predicted)
• pka: 9.45±0.43(Predicted)
• InChIKey: SWIWEMMZHYDBHD-XZWHSSHBSA-N
• SMILES: C(NC1=NC(OCCC#N)=C2C(=N1)N([C@@H]1O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C1)C=N2)(=O)C(C)C

N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine Usage And Synthesis

Description

N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine is a nucleoside, ribonucleoside, and anti-cancer drug. It is modified with two acyl groups at the 2′ position of the sugar moiety and contains a phosphoramidite group in the 5′ position. It is an activator of DNA synthesis in vitro. In vivo studies have shown that N2-Isobutyryl O6 cyanoethyl 7' OH N trityl morpholino guanine can be used as an anticancer agent against human breast cancer cells.