Introduction:Basic information about N-Benzoyl-2'-deoxy-adenosine CAS 4546-72-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
N-Benzoyl-2'-deoxy-adenosine Basic information
| Product Name: | N-Benzoyl-2'-deoxy-adenosine |
| Synonyms: | N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-6-purinyl]benzamide;DA-BZ;N6-BZ-2'-DEOXYADENOSINE;N6-BENZOYLDEOXYADENOSINE;N-BZ-DA;n-benzoyl-2'-deoxy-adenosine;n-benzoyl-2’-deoxy-adenosin;BZ-DEOXYADENOSINE |
| CAS: | 4546-72-9 |
| MF: | C17H17N5O4 |
| MW: | 355.35 |
| EINECS: | 224-903-6 |
| Product Categories: | Nucleic acids;Modified(deoxy)nucleoside |
| Mol File: | 4546-72-9.mol |
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N-Benzoyl-2'-deoxy-adenosine Chemical Properties
| Melting point | 120-122C |
| density | 1.61±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml |
| pka | 7.87±0.43(Predicted) |
| form | A crystalline solid |
| color | White to off-white |
| Water Solubility | Soluble in water (slightly), and methanol (20 mg/ml). |
| CAS DataBase Reference | 4546-72-9(CAS DataBase Reference) |
Safety Information
| Safety Statements | 24/25 |
| HS Code | 29349990 |
N-Benzoyl-2'-deoxy-adenosine Usage And Synthesis
| Description | N-Benzoyl-2'-deoxyadenosine is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. N-Benzoyl-2'-deoxyadenosine binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. N-Benzoyl-2'-deoxyadenosine has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. |
| Uses | Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine. |
N-Benzoyl-2'-deoxy-adenosine Preparation Products And Raw materials
| Preparation Products | N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine |