n-Butyl carbamate CAS 592-35-8

Introduction：Basic information about n-Butyl carbamate CAS 592-35-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

n-Butyl carbamate Basic information

• Product Name: n-Butyl carbamate
• Synonyms: usafel-101;usaffo-1;BUTYL CARBAMATE;CARBAMIC ACID N-BUTYL ESTER;n-Butylcarbamate,98+%;N-BUTYLCARBAMICACID;n-Butyl carbamate,97%;Butyl carbaMate 98%
• CAS: 592-35-8
• MF: C5H11NO2
• MW: 117.15
• EINECS: 209-751-0
• Product Categories: Building Blocks;Chemical Synthesis;Pharmaceutical Intermediates;Nitrogen Compounds;Organic Building Blocks;Protected Amines;Nitrogen Compounds;Organic Building Blocks;Protected Amines
• Mol File: 592-35-8.mol

n-Butyl carbamate Chemical Properties

• Melting point: 53-55 °C (lit.)
• Boiling point: 204 °C
• density: 0.9308 (estimate)
• vapor pressure: 2.65hPa at 20℃
• refractive index: 1.4189 (estimate)
• Fp: 228 °F
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: SOLUBLE
• pka: 13.52±0.50(Predicted)
• form: powder to crystal
• color: White to Almost white
• Water Solubility: SOLUBLE
• InChI: 1S/C5H11NO2/c1-2-3-4-8-5(6)7/h2-4H2,1H3,(H2,6,7)
• InChIKey: SKKTUOZKZKCGTB-UHFFFAOYSA-N
• SMILES: CCCCOC(N)=O
• LogP: 2.75 at 25℃
• CAS DataBase Reference: 592-35-8(CAS DataBase Reference)
• NIST Chemistry Reference: Butyl carbamate(592-35-8)
• EPA Substance Registry System: Carbamic acid, butyl ester (592-35-8)

Safety Information

• Hazard Codes: Xn,Xi,F
• Risk Statements: 22-41-43-36/37/38-10-36-20/21/22
• Safety Statements: 26-36/37/39-24/25-16-7/9-36/37
• WGK Germany: 1
• RTECS: EZ0175000
• TSCA: TSCA listed
• HS Code: 29241990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral Eye Dam. 1 Skin Sens. 1
• Hazardous Substances Data: 592-35-8(Hazardous Substances Data)

n-Butyl carbamate Usage And Synthesis

Chemical Properties

WHITE FLAKES

Flammability and Explosibility

Not classified

Safety Profile

A poison via intraperitoneal route. Moderately toxic via subcutaneous route. Experimental teratogenic effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. See also CARBAMATES. When heated to decomposition it emits toxic fumes of NOx

Synthesis

57-13-6

71-36-3

592-35-8

542-52-9

GENERAL STEPS: First, the catalyst was prepared by calcining Yb(NO3)3-6H2O in air at 350 °C for 4 hours. Subsequently, 48.0 g of n-butanol, 6.0 g of urea and 0.75 g of the above prepared catalyst were added to an autoclave. The reaction was carried out at 180°C for 6 hours under autogenous pressure (about 8.5 atm). At the end of the reaction, the yields of dibutyl carbonate (DBC) and butyl carbamate (BC) were 43.1% by weight and 12.8% by weight, respectively.

References

[1] RSC Advances, 2015, vol. 5, # 25, p. 19534 - 19540
[2] RSC Advances, 2015, vol. 5, # 25, p. 19534 - 19540
[3] Patent: US2010/312001, 2010, A1. Location in patent: Page/Page column 4
[4] Patent: TW2017/31810, 2017, A. Location in patent: Paragraph 0080

n-Butyl carbamate Preparation Products And Raw materials

• Raw materials: Urea-->1-Butanol