Introduction：Basic information about N-TERT-BUTYLACRYLAMIDE CAS 107-58-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
N-TERT-BUTYLACRYLAMIDE Basic information
| Product Name: | N-TERT-BUTYLACRYLAMIDE |
| Synonyms: | TBA;N-T-BUTYLACRYLAMIDE;N-TERT-BUTYLACRYLAMIDE;N-ACRYLOYL-TERT-BUTYLAMINE;TIMTEC-BB SBB008122;Acrylamide, N-tert-butyl-;N-tert-butylprop-2-enamide;N- tertiary Butylacrylamide |
| CAS: | 107-58-4 |
| MF: | C7H13NO |
| MW: | 127.18 |
| EINECS: | 203-505-6 |
| Product Categories: | Acrylamide and Methacrylamide;Acrylic Monomers;Monomers;107-58-4 |
| Mol File: | 107-58-4.mol |
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N-TERT-BUTYLACRYLAMIDE Chemical Properties
| Melting point | 126-129 °C (lit.) |
| Boiling point | 235.98°C (rough estimate) |
| density | 1.0083 (rough estimate) |
| vapor pressure | 0.385Pa at 25℃ |
| refractive index | 1.4830 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 3.8g/L in organic solvents at 20 ℃ |
| pka | 15.11±0.46(Predicted) |
| form | Powder or Chunks |
| color | White to off-white |
| Water Solubility | 1g/L at 30℃ |
| BRN | 1742331 |
| InChI | 1S/C7H13NO/c1-5-6(9)8-7(2,3)4/h5H,1H2,2-4H3,(H,8,9) |
| InChIKey | XFHJDMUEHUHAJW-UHFFFAOYSA-N |
| SMILES | CC(C)(C)NC(=O)C=C |
| LogP | 1.45 at 25℃ |
| CAS DataBase Reference | 107-58-4(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Propenamide, N-(1,1-dimethylethyl)- (107-58-4) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-36/37 |
| WGK Germany | 3 |
| RTECS | AS3460000 |
| TSCA | TSCA listed |
| HazardClass | IRRITANT |
| HS Code | 29241990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
N-TERT-BUTYLACRYLAMIDE Usage And Synthesis
| Uses | N-tert-Butylacrylamide is used for study on abiotic anti-VEGF nanoparticle for anti-angiogenic cancer therapy. |
| Chemical Properties | white to off-white powder or chunks |
| Uses | nTBA is temperature sensitive monomers that can be potentially used in drug delivery systems, dewatering of proteins, and immobilization of cells. It can be used in the preparation of poly(nTBA) based copolymeric hydrogels for bovin serum albumin. |
| Uses | N-tert-Butylacrylamide is used for study on abiotic anti-VEGF nanoparticle for anti-angiogenic cancer therapy (1,2). |
| General Description | N-tert-Butylacrylamide (nTBA) belongs to the class of hydrophobic acrylamides which can be synthesized by Ritter reaction and optimized by using N-tert-butyl acetate and acetic acid. |
| Flammability and Explosibility | Non flammable |
N-TERT-BUTYLACRYLAMIDE Preparation Products And Raw materials
| Raw materials | 2-Acrylamide-2-methylpropanesulfonic acid-->L-Lysine-->tert-Butanol-->Di-tert-butyl dicarbonate-->Phenothiazine-->tert-Butyl acetate-->Acrylamide-->tert-Butylamine-->Isobutylene-->Propionitrile-->Acryloyl chloride |
