CAS 76931-93-6|N-Succinimidyl-S-acetylthioacetate
| Common Name | N-Succinimidyl-S-acetylthioacetate | ||
|---|---|---|---|
| CAS Number | 76931-93-6 | Molecular Weight | 231.226 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 337.3±44.0 °C at 760 mmHg |
| Molecular Formula | C8H9NO5S | Melting Point | 84-89ºC |
| MSDS | ChineseUSA | Flash Point | 157.8±28.4 °C |
Names
| Name | (2,5-dioxopyrrolidin-1-yl) 2-acetylsulfanylacetate |
|---|---|
| Synonym | More Synonyms |
N-Succinimidyl-S-acetylthioacetate BiologicalActivity
| Description | N-Succinimidyl S-acetylthioacetate (SATA), a protein modification agent, introduces thiol-groups into protein molecules. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form[1][2]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. J.L.M.Heeremans, et al. Interference of ϵ-amino-caproic acid with [N-succinimidyl S-acetylthioacetate derived] thiol-introduction into glu-plasminogen. Volume 8, Supplement 2, 1994, Pages 138-141. [2]. Allen KJH, et al. Evaluation of N-Succinimidyl S-Acetylthioacetate Ligand for Radiolabeling of HumanizedAntibodies with 188Rhenium. Cancer Biother Radiopharm. 2018 Oct;33(8):349-355. |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 337.3±44.0 °C at 760 mmHg |
| Melting Point | 84-89ºC |
| Molecular Formula | C8H9NO5S |
| Molecular Weight | 231.226 |
| Flash Point | 157.8±28.4 °C |
| Exact Mass | 231.020142 |
| PSA | 106.05000 |
| LogP | -1.16 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.562 |
| InChIKey | FLCQLSRLQIPNLM-UHFFFAOYSA-N |
| SMILES | CC(=O)SCC(=O)ON1C(=O)CCC1=O |
| Storage condition | -20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2930909090 |
Customs
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| N-Succinimidyl S-acetylthioglycolate |
| S-Acetylthioglycolic acid N-hydroxysuccinimide ester |
| S-acetylthioacetic acid N-hydroxysuccinimidyl ester |
| 2,5-Dioxopyrrolidin-1-yl 2-(acetylthio)acetate |
| MFCD00036891 |
| Ethanethioic acid, S-(2-((2,5-dioxo-1-pyrrolidinyl)oxy)-2-oxoethyl) ester |
| S-{2-[(2,5-Dioxopyrrolidin-1-yl)oxy]-2-oxoethyl} ethanethioate |
| N-succinimidyl S-Acetylthioacetate |
| Ethanethioic acid, S-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl] ester |
| S-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl} ethanethioate |
| 2,5-dioxopyrrolidin-1-yl 2-(acetylsulfanyl)acetate |
| SATA |
| HSATA |
| N-hydroxysuccinimide S-acetylthioacetate |
