CAS 2954-50-9|2-Aminotetralin

Introduction：Basic information about CAS 2954-50-9|2-Aminotetralin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Synonyms

Common Name	2-Aminotetralin
CAS Number	2954-50-9	Molecular Weight	147.217
Density	1.0±0.1 g/cm3	Boiling Point	250.7±29.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₃N	Melting Point	149-151 °C
MSDS	/	Flash Point	111.6±19.6 °C

Names

Name	1,2,3,4-tetrahydro-2-naphthylamine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	250.7±29.0 °C at 760 mmHg
Melting Point	149-151 °C
Molecular Formula	C₁₀H₁₃N
Molecular Weight	147.217
Flash Point	111.6±19.6 °C
Exact Mass	147.104797
PSA	26.02000
LogP	2.09
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.561
InChIKey	LCGFVWKNXLRFIF-UHFFFAOYSA-N
SMILES	NC1CCc2ccccc2C1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QM4900000

CHEMICAL NAME :: 2-Naphthylamine, 1,2,3,4-tetrahydro-

CAS REGISTRY NUMBER :: 2954-50-9

BEILSTEIN REFERENCE NO. :: 1102357

LAST UPDATED :: 199612

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C10-H13-N

MOLECULAR WEIGHT :: 147.24

WISWESSER LINE NOTATION :: L66&TJ HZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,466,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,466,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Human

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - sleep Behavioral - hallucinations, distorted perceptions

REFERENCE :: APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher information, see VAAPB7. Volume(issue)/page/year: 115,14,1889

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - sleep Behavioral - hallucinations, distorted perceptions

REFERENCE :: APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher information, see VAAPB7. Volume(issue)/page/year: 115,14,1889

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 64 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 61,168,1965

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Vascular - regional or general arteriolar constriction Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 35,70,1928

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher information, see VAAPB7. Volume(issue)/page/year: 115,14,1889

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 61,168,1965

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 375 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher information, see VAAPB7. Volume(issue)/page/year: 115,14,1889 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 20 mg/kg

SEX/DURATION :: female 5 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Newborn - stillbirth

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 100,555,1959

Safety Information

Risk Phrases	R36/37/38
Safety Phrases	26-36/37/39
HS Code	2921450090

Customs

HS Code	2921450090
Summary	2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Synonyms

1-Naphthalenol,1,2,3,4-tetrahydro-,benzoate

1-Benzoyloxy-1.2.3.4-tetrahydro-naphthalin

1,2,3,4-tetrahydronaphth-2-ylamine

2-Aminotetralin

Aminotetralin

1,2,3,4-tetrahydronaphthalen-1-yl benzoate

2-amino-1,2,3,4-tetrahydronaphthalene

1,2,3,4-Tetrahydro-2-naphthalenamine

2-amino-tetralin

2-R-amino-tetraline

2-Naphthalenamine, 1,2,3,4-tetrahydro-

1,2,3,4-tetrahydro-1-naphthyl benzoate

THN

1,2,3,4-Tetrahydronaphthalen-2-amine

1,2,3,4-tetrahydro-naphth-1-yl benzoate

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