CAS 60569-19-9|1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE

Introduction:Basic information about CAS 60569-19-9|1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE
CAS Number60569-19-9Molecular Weight367.48
Density1.08 g/cm3Boiling Point468.8ºC at 760 mmHg
Molecular FormulaC23H29NO3Melting Point/
MSDS/Flash Point134.6ºC

Names

Name(1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate
SynonymMore Synonyms

BiologicalActivity

DescriptionPropiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2].
Related CatalogSignaling Pathways >>Neuronal Signaling >>mAChRSignaling Pathways >>GPCR/G Protein >>mAChRResearch Areas >>Neurological Disease
References

[1]. McKeage K. Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms. Clin Drug Investig. 2013 Jan;33(1):71-91.

[2]. Madersbacher H, Mürtz G. Efficacy, tolerability and safety profile of propiverine in the treatment of the overactive bladder (non-neurogenic and neurogenic). World J Urol. 2001 Nov;19(5):324-35.

Chemical & Physical Properties

Density1.08 g/cm3
Boiling Point468.8ºC at 760 mmHg
Molecular FormulaC23H29NO3
Molecular Weight367.48
Flash Point134.6ºC
Exact Mass367.21500
PSA38.77000
LogP3.93210
Index of Refraction1.57
InChIKeyQPCVHQBVMYCJOM-UHFFFAOYSA-N
SMILESCCCOC(C(=O)OC1CCN(C)CC1)(c1ccccc1)c1ccccc1

Safety Information

HS Code2933399090

Customs

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Propiverine
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