CAS 17615-73-5|5-amino-2-(4-aminophenyl)sulfonylbenzenesulfonamide

Introduction：Basic information about CAS 17615-73-5|5-amino-2-(4-aminophenyl)sulfonylbenzenesulfonamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Synonyms

Common Name	5-amino-2-(4-aminophenyl)sulfonylbenzenesulfonamide
CAS Number	17615-73-5	Molecular Weight	327.37900
Density	1.549g/cm3	Boiling Point	686.1ºC at 760mmHg
Molecular Formula	C₁₂H₁₃N₃O₄S₂	Melting Point	/
MSDS	/	Flash Point	368.7ºC

Names

Name	5-amino-2-(4-aminophenyl)sulfonylbenzenesulfonamide
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.549g/cm3
Boiling Point	686.1ºC at 760mmHg
Molecular Formula	C₁₂H₁₃N₃O₄S₂
Molecular Weight	327.37900
Flash Point	368.7ºC
Exact Mass	327.03500
PSA	163.10000
LogP	4.35550
Vapour Pressure	1.12E-18mmHg at 25°C
Index of Refraction	1.681
InChIKey	JDZPLYBLBIKFHJ-UHFFFAOYSA-N
SMILES	Nc1ccc(S(=O)(=O)c2ccc(N)cc2S(N)(=O)=O)cc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OY2230000

CHEMICAL NAME :: Metanilamide, 6-sulfanilyl-

CAS REGISTRY NUMBER :: 17615-73-5

BEILSTEIN REFERENCE NO. :: 3435880

LAST UPDATED :: 199612

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C12-H13-N3-O4-S2

MOLECULAR WEIGHT :: 327.40

WISWESSER LINE NOTATION :: ZSWR CZ FSWR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >6 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - other changes

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >6 gm/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Blood - pigmented or nucleated red blood cells Blood - changes in leukocyte (WBC) count

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5150 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Skin and Appendages - hair

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Mammal - pig

DOSE/DURATION :: >213 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 24 gm/kg

SEX/DURATION :: female 9-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 9,695,1975

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1800 mg/kg

SEX/DURATION :: female 9-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 9,695,1975

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 120 mg/kg

SEX/DURATION :: female 9-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 9,695,1975

Safety Information

HS Code	2935009090

Customs

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Synonyms

Sulfamoyldapsone

5-Amino-2-sulfanilyl-benzolsulfonsaeure-amid

Metanilamide,6-sulfanilyl

6-(p-Anilinosulfonyl)metanilamide

5-Amino-2-(4-amino-phenylsulfon)-benzolsulfonamid-(1)

SDDS

5-amino-2-[(4-aminophenyl)sulfonyl]benzenesulfonamide

2-Sulfamonyl-4,4'-diaminophenylsulfone

2-Sulfamonyl-4,4'-diaminodiphenyl-sulfone

5-amino-2-sulfanilyl-benzenesulfonic acid amide

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