Introduction：Basic information about CAS 6054-10-0|Braylin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Braylin |
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| CAS Number | 6054-10-0 | Molecular Weight | 258.269 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 441.2±45.0 °C at 760 mmHg |
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| Molecular Formula | C15H14O4 | Melting Point | / |
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| MSDS | / | Flash Point | 198.5±28.8 °C |
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Names
| Name | N'-[(Z)-indol-3-ylidenemethyl]-1-(4-methoxyphenyl)-5-oxopyrrolidine-3-carbohydrazide |
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| Synonym | More Synonyms |
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Braylin BiologicalActivity
| Description | Braylin, a coumarin, is a potent phosphodiesterase-4 (PDE4) inhibitor and is involved in anti-inflammatory and immunomodulation, which may serve as a potential target for the study of immunoinflammatory diseases[1]. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE)Research Areas >>Inflammation/Immunology |
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| References | [1]. Renan Fernandes Espírito-Santo, et al. The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches. PLoS One. 2017 Jun 8;12(6):e0179174. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 441.2±45.0 °C at 760 mmHg |
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| Molecular Formula | C15H14O4 |
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| Molecular Weight | 258.269 |
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| Flash Point | 198.5±28.8 °C |
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| Exact Mass | 258.089203 |
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| PSA | 48.67000 |
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| LogP | 3.15 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.570 |
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| InChIKey | UOFNVZWWIXXTMZ-UHFFFAOYSA-N |
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| SMILES | COc1cc2ccc(=O)oc2c2c1OC(C)(C)C=C2 |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2932999099 |
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Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 6-methoxyseselin |
| 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one, 6-methoxy-8,8-dimethyl- |
| 6-Methoxy-8,8-dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one |
| HMS2622L11 |
