CAS 531-57-7|3-Amino-7-(methylamino)phenothiazin-5-ium chloride
Introduction：Basic information about CAS 531-57-7|3-Amino-7-(methylamino)phenothiazin-5-ium chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Azure C is the product of sequential enzymatic oxidation of Methylene blue (MB) or Azure B (AB). Azure C serves as the substrate of horseradish peroxidase (HRP)[1][2].
Related Catalog
Research Areas >>OthersSignaling Pathways >>Others >>Others
References
[1]. Ferreira-Leitão V S, et al. Methylene blue and azure B oxidation by horseradish peroxidase: a comparative evaluation of class II and class III peroxidases. Applied Catalysis B: Environmental, 2003, 42(2): 213-221.
[2]. Lo Cascio F, et al. Azure C Targets and Modulates Toxic Tau Oligomers. ACS Chem Neurosci. 2018 Jun 20;9(6):1317-1326.
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1536 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 36 (estimated) No. of Female Employees: 16 (estimated)
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles8
More Articles
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Bioorg. Med. Chem. Lett. 19 , 4952-7, (2009)
Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular oligome...
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct.
J. Biol. Chem. 282 , 10311-24, (2007)
Alzheimer disease is characterized by the abnormal aggregation of amyloid beta peptide into extracellular fibrillar deposits known as amyloid plaques. Soluble oligomers have been observed at early tim...
Note from the Biological Stain Commission: revision of azure B assay protocol.
