CAS 10378-23-1|Ethylenediaminetetraacetic acid sodium hydrate
| Common Name | Ethylenediaminetetraacetic acid sodium hydrate | ||
|---|---|---|---|
| CAS Number | 10378-23-1 | Molecular Weight | 416.201 |
| Density | / | Boiling Point | 614.2ºC at 760mmHg |
| Molecular Formula | C10H16N2Na4O10 | Melting Point | >300ºC |
| MSDS | ChineseUSA | Flash Point | 325.2ºC |
| Symbol | GHS05, GHS07 | Signal Word | Danger |
Names
| Name | Ethylenediaminetetraacetic acid tetrasodium salt dihydrate |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid sodium hydrate can also decrease the formation of disulfide bonds[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
| References | [1]. Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9. [2]. Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 2007;45(5):565-76. [3]. Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb;10(1):58-62. |
Chemical & Physical Properties
| Boiling Point | 614.2ºC at 760mmHg |
|---|---|
| Melting Point | >300ºC |
| Molecular Formula | C10H16N2Na4O10 |
| Molecular Weight | 416.201 |
| Flash Point | 325.2ºC |
| Exact Mass | 416.039581 |
| PSA | 185.46000 |
| Storage condition | Store at RT. |
| Water Solubility | H2O: clear, colorless |
Safety Information
| Symbol | GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | DB6145180 |
| HS Code | 29224995 |
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Synonyms
| Ethylenediaminetetraacetic acid tetrasodium salt |
| Sodium 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetraacetate hydrate (4:1:2) |
| Ethylenediaminetetraacetic Acid Tetrasodium Salt Dihydrate |
| EDTA 4Na Dihydrate |
| Tetrasodium ethylenediaminetetraacetate dihydrate |
| Sodium 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate hydrate (4:1:2) |
| EDTA-4Na.2H2O |
| EDTA tetrasodium salt |
| EINECS 208-924-8 |
| MFCD00007499 |
