CAS 1764-85-8|2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-[[(2,2,2-trifluo

Introduction:Basic information about CAS 1764-85-8|2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-[[(2,2,2-trifluo, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-[[(2,2,2-trifluoroethyl)thio]methyl]-, 1,1-dioxide
CAS Number1764-85-8Molecular Weight425.85500
Density1.636g/cm3Boiling Point586.6ºC at 760mmHg
Molecular FormulaC10H11ClF3N3O4S3Melting Point/
MSDS/Flash Point308.6ºC

Names

Name6-chloro-1,1-dioxo-3-(2,2,2-trifluoroethylsulfanylmethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
SynonymMore Synonyms

BiologicalActivity

DescriptionEpitizide, a benzothiadiazine, commonly found in combination Triamterene, is used to produce diuresis[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease
References

[1]. K Deventer, et al. Screening for 18 diuretics and probenecid in doping analysis by liquid chromatography-tandem mass spectrometry. Biomed Chromatogr. 2002 Dec;16(8):529-35.

Chemical & Physical Properties

Density1.636g/cm3
Boiling Point586.6ºC at 760mmHg
Molecular FormulaC10H11ClF3N3O4S3
Molecular Weight425.85500
Flash Point308.6ºC
Exact Mass424.95500
PSA160.42000
LogP4.64150
Vapour Pressure9.64E-14mmHg at 25°C
Index of Refraction1.566
InChIKeyRINBGYCKMGDWPY-UHFFFAOYSA-N
SMILESNS(=O)(=O)c1cc2c(cc1Cl)NC(CSCC(F)(F)F)NS2(=O)=O

Safety Information

HS Code2935009090

Customs

HS Code2935009090
Summary2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Synonyms

Epitizid
Epitizide
Epitizidum
P 2105
EPITHIAZIDE
Epithiazide [USAN]
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