CAS 108-43-0|3-Chlorophenol
Introduction：Basic information about CAS 108-43-0|3-Chlorophenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3-Chlorophenol | ||
|---|---|---|---|
| CAS Number | 108-43-0 | Molecular Weight | 128.556 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 214.0±0.0 °C at 760 mmHg |
| Molecular Formula | C6H5ClO | Melting Point | 31-34 °C(lit.) |
| MSDS | USA | Flash Point | 76.9±19.8 °C |
| Symbol | GHS07, GHS09 | Signal Word | Warning |
Names
| Name | 3-chlorophenol |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 214.0±0.0 °C at 760 mmHg |
| Melting Point | 31-34 °C(lit.) |
| Molecular Formula | C6H5ClO |
| Molecular Weight | 128.556 |
| Flash Point | 76.9±19.8 °C |
| Exact Mass | 128.002899 |
| PSA | 20.23000 |
| LogP | 2.40 |
| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
| Index of Refraction | 1.576 |
| Stability | Stable. Combustible. Incompatible with acid chlorides, oxidizing agents, acid anhydrides. Discolours in air. |
| Water Solubility | 27.7 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 570 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 355 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature increase
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1390 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 521 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6000 mg/kg/15W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
MUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 10 ug/plate
- REFERENCE :
- TECSDY Toxicological and Environmental Chemistry. (Gordon & Breach Science Pub. Inc., 1 Park Ave., New York, NY 10016) V.3(3/4)- 1981- Volume(issue)/page/year: 14,143,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4138 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 919 (estimated) No. of Female Employees: 306 (estimated)
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 10 ug/plate
- REFERENCE :
- TECSDY Toxicological and Environmental Chemistry. (Gordon & Breach Science Pub. Inc., 1 Park Ave., New York, NY 10016) V.3(3/4)- 1981- Volume(issue)/page/year: 14,143,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4138 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 919 (estimated) No. of Female Employees: 306 (estimated)
Safety Information
| Symbol | GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H332-H411 |
| Precautionary Statements | P273-P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R20/21/22;R51/53 |
| Safety Phrases | S28-S61-S28A |
| RIDADR | UN 2020 6.1/PG 3 |
| WGK Germany | 2 |
| RTECS | SK2450000 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 29081000 |
Customs
| HS Code | 2908199090 |
|---|---|
| Summary | HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0% |
Articles34
More Articles| Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins Bioorg. Med. Chem. 17 , 896-904, (2009) This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoret... | |
| Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). J. Med. Chem. 48 , 3269-79, (2005) Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm... | |
| Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study. J. Med. Chem. 48 , 7234-42, (2005) In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas... |
Synonyms
| 1-Chloro-3-hydroxybenzene |
| m-Chlorophenol |
| 3-Chloro-1-hydroxybenzene |
| Phenol,3-chloro |
| meta-chlorophenol |
| m-Chlorophenic acid |
| 5-chlorophenol |
| Phenol, 3-chloro- |
| EINECS 203-582-6 |
| m-Cl-phenol |
| 3-chloro-phenol |
| QR CG |
| 3-Hydroxychlorobenzene |
| 3-Chlorophenol |
| Phenol,m-chloro |
| MFCD00002256 |
| meta-monochlorophenol |
| m-monochlorophenol |
