Introduction：Basic information about CAS 664-95-9|Benzenesulfonamide,N-[(cyclohexylamino)carbonyl]-4-methyl-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Benzenesulfonamide,N-[(cyclohexylamino)carbonyl]-4-methyl- |
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| CAS Number | 664-95-9 | Molecular Weight | 296.39 |
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| Density | 1.26g/cm3 | Boiling Point | / |
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| Molecular Formula | C14H20N2O3S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-cyclohexyl-3-(4-methylphenyl)sulfonylurea |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Cyclamide (Cicloral), an oligopeptide, can be produced by cyanobacteria algae strains. Cyclamide can be used for the research of diabetes mellitus[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| References | [1]. GRINCHENKO TS, et, al. CYCLAMIDE (K-386) TREATMENT OF DIABETES MELLITUS. Fed Proc Transl Suppl. Jul-Aug 1964;23:767-8. [2]. Natumi R, et, al. Cyanobacterial Toxins and Cyanopeptide Transformation Kinetics by Singlet Oxygen and pH-Dependence in Sunlit Surface Waters. Environ Sci Technol. 2021 Nov 16;55(22):15196-15205. |
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Chemical & Physical Properties
| Density | 1.26g/cm3 |
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| Molecular Formula | C14H20N2O3S |
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| Molecular Weight | 296.39 |
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| Exact Mass | 296.11900 |
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| PSA | 83.65000 |
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| LogP | 4.17820 |
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| Index of Refraction | 1.578 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- YS7800000
- CHEMICAL NAME :
- Urea, 1-cyclohexyl-3-(p-tolylsulfonyl)-
- CAS REGISTRY NUMBER :
- 664-95-9
- BEILSTEIN REFERENCE NO. :
- 1995860
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H20-N2-O3-S
- MOLECULAR WEIGHT :
- 296.42
- WISWESSER LINE NOTATION :
- L6TJ AMVMSWR D1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 870 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 12,268,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,280,1970 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 800 mg/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 28,616,1965
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Synonyms
| Glicosil |
| TOLCYCLAMIDE |
| Gliciclamide |
| 1-cyclohexyl-3-tosylurea |
| Cyclamide |
| Glycyclamid |
| N-cyclohexyl-N'-(toluene-4-sulfonyl)-urea |
| Agliral |
| Cyclamid |
| N-Cyclohexyl-N'-(toluol-4-sulfonyl)-harnstoff |
| Cychloral |
| N1-p-Toluolsulfonyl-N2-cyclohexylharnstoff |
| Glycyclamide |
| Tolhexamide |
| N-(cyclohexylcarbamoyl)-4-methylbenzenesulfonamide |
