CAS 88-18-6|2-tert-Butylphenol
Introduction：Basic information about CAS 88-18-6|2-tert-Butylphenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-tert-Butylphenol | ||
|---|---|---|---|
| CAS Number | 88-18-6 | Molecular Weight | 150.218 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 221.0±0.0 °C at 760 mmHg |
| Molecular Formula | C10H14O | Melting Point | −7 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 98.9±8.2 °C |
| Symbol | GHS05, GHS06, GHS09 | Signal Word | Danger |
Names
| Name | 2-tert-Butylphenol |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 221.0±0.0 °C at 760 mmHg |
| Melting Point | −7 °C(lit.) |
| Molecular Formula | C10H14O |
| Molecular Weight | 150.218 |
| Flash Point | 98.9±8.2 °C |
| Exact Mass | 150.104462 |
| PSA | 20.23000 |
| LogP | 3.17 |
| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
| Index of Refraction | 1.514 |
| InChIKey | WJQOZHYUIDYNHM-UHFFFAOYSA-N |
| SMILES | CC(C)(C)c1ccccc1O |
| Water Solubility | 0.23 g/100 mL (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 82 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9086 ng/kg/12D-I
- TOXIC EFFECTS :
- Liver - other changes Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
- REFERENCE :
- BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 45,935,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1072 No. of Facilities: 221 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 8300 (estimated) No. of Female Employees: 239 (estimated)
Safety Information
| Symbol | GHS05, GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H311-H314-H330-H400 |
| Precautionary Statements | P260-P273-P280-P284-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T:Toxic;N:Dangerousfortheenvironment; |
| Risk Phrases | R22;R23;R34;R51/53 |
| Safety Phrases | S26-S36/37/39-S45-S61 |
| RIDADR | UN 2922 8/PG 2 |
| WGK Germany | 2 |
| RTECS | SJ8921000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 29071900 |
Customs
| HS Code | 2907199090 |
|---|---|
| Summary | 2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
Articles9
More Articles| Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). J. Med. Chem. 48 , 3269-79, (2005) Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm... | |
| Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study. J. Med. Chem. 48 , 7234-42, (2005) In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas... | |
| Isolation and characterization of a novel 2-sec-butylphenol-degrading bacterium Pseudomonas sp. strain MS-1. Biodegradation 21(2) , 157-65, (2010) A novel bacterium capable of utilizing 2-sec-butylphenol as the sole carbon and energy source, Pseudomonas sp. strain MS-1, was isolated from freshwater sediment. Within 30 h, strain MS-1 completely d... |
Synonyms
| EINECS 201-807-2 |
| 2-tert-Butyl phen01 |
| 2-(2-Methyl-2-propanyl)phenol |
| o-tert-butyl-pheno |
| 2-t-Butylphenol |
| O-T-BUTYLPHENOL |
| o-tert-butylphenol |
| o-reft-Butyl phenol |
| ortho-tert-butylphenol |
| Butylphenol |
| 2-tert-Butylphenol |
| Phenol, (1,1-dimethylethyl)- |
| 2-t-BuC6H4OH |
| OTBP |
| Phenol, 2-(1,1-dimethylethyl)- |
| MFCD00002223 |
