CAS 69504-14-9|3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE

Introduction:Basic information about CAS 69504-14-9|3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE
CAS Number69504-14-9Molecular Weight381.50
Density/Boiling Point/
Molecular FormulaC16H27N5O4SiMelting Point/
MSDS/Flash Point/

Names

Name[(2S,3R,4S,5R)-2-(6-aminopurin-9-yl)-3-hydroxy-5-(hydroxymethyl)-4-[(2-methylpropan-2-yl)oxy]oxolan-2-yl]-dimethylsilicon
SynonymMore Synonyms

3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE BiologicalActivity

Description3’-O-t-Butyldimethylsilyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

Molecular FormulaC16H27N5O4Si
Molecular Weight381.50
Exact Mass381.18300
PSA128.54000
LogP1.63070
InChIKeyQPARFARLOLAARR-SDBHATRESA-N
SMILESCC(C)(C)[Si](C)(C)OC1C(CO)OC(n2cnc3c(N)ncnc32)C1O

Synonyms

O3'-(tert-butyl-dimethyl-silanyl)-adenosine
3'-O-(tert-butyldimethylsilyl)adenosine
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CAS 81352-25-2|5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-ADENOSINE
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