Introduction:Basic information about CAS 69504-14-9|3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE |
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| CAS Number | 69504-14-9 | Molecular Weight | 381.50 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C16H27N5O4Si | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | [(2S,3R,4S,5R)-2-(6-aminopurin-9-yl)-3-hydroxy-5-(hydroxymethyl)-4-[(2-methylpropan-2-yl)oxy]oxolan-2-yl]-dimethylsilicon |
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| Synonym | More Synonyms |
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3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE BiologicalActivity
| Description | 3’-O-t-Butyldimethylsilyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. |
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Chemical & Physical Properties
| Molecular Formula | C16H27N5O4Si |
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| Molecular Weight | 381.50 |
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| Exact Mass | 381.18300 |
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| PSA | 128.54000 |
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| LogP | 1.63070 |
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| InChIKey | QPARFARLOLAARR-SDBHATRESA-N |
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| SMILES | CC(C)(C)[Si](C)(C)OC1C(CO)OC(n2cnc3c(N)ncnc32)C1O |
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Synonyms
| O3'-(tert-butyl-dimethyl-silanyl)-adenosine |
| 3'-O-(tert-butyldimethylsilyl)adenosine |