Introduction：Basic information about CAS 62595-14-6|L-Tyrosine (Ring-D4), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | L-Tyrosine (Ring-D4) |
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| CAS Number | 62595-14-6 | Molecular Weight | 185.213 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 385.2±32.0 °C at 760 mmHg |
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| Molecular Formula | C9H7D4NO3 | Melting Point | >300ºC (dec.)(lit.) |
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| MSDS | ChineseUSA | Flash Point | 186.7±25.1 °C |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | L-4-Hydroxyphenyl-2,3,5,6-d4-alanine |
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| Synonym | More Synonyms |
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L-Tyrosine (Ring-D4) BiologicalActivity
| Description | L-Tyrosine D4 is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| In Vitro | L-Tyrosine inhibits citrate synthase activity in the posterior cortex (2.0 and 4.0 mM), malate dehydrogenase is not altered by L-Tyrosine and succinate dehydrogenase is increased in the posterior cortex (0.1-4.0 mM), hippocampus (1.0-4.0 mM), striatum (4.0 mM) and liver (0.1-4.0 mM)[1]. |
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| References | [1]. Ferreira GK, et al. Effect of L-tyrosine in vitro and in vivo on energy metabolism parameters in brain and liver of young rats. Neurotox Res. 2013 May;23(4):327-35. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 385.2±32.0 °C at 760 mmHg |
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| Melting Point | >300ºC (dec.)(lit.) |
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| Molecular Formula | C9H7D4NO3 |
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| Molecular Weight | 185.213 |
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| Flash Point | 186.7±25.1 °C |
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| Exact Mass | 185.098999 |
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| PSA | 83.55000 |
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| LogP | 0.38 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.614 |
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| InChIKey | OUYCCCASQSFEME-FCDGGRDXSA-N |
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| SMILES | NC(Cc1ccc(O)cc1)C(=O)O |
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| Storage condition | 2-8°C |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xi |
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| Risk Phrases | 36/37/38 |
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| Safety Phrases | 26-36 |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| (2S)-2-amino-3-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)propanoic acid |
| L-(2,3,5,6-H)Tyrosine |
| L-4-Hydroxyphenyl-d4-alanine |
| L-TYROSINE-2,3,5,6-D4 |
| L-4-Hydroxyphenyl-2,3,5,6-d4-alanine |
| MFCD00079605 |
| L-Tyrosine-2,3,5,6-d |
