CAS 62948-75-8|Uric acid-15N2
Introduction：Basic information about CAS 62948-75-8|Uric acid-15N2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Uric acid-15N2 | ||
|---|---|---|---|
| CAS Number | 62948-75-8 | Molecular Weight | 170.09700 |
| Density | 1.87g/cm3 | Boiling Point | / |
| Molecular Formula | C5H4N4O3 | Melting Point | >300ºC(lit.) |
| MSDS | USA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 7,9-dihydro-3H-purine-2,6,8-trione |
|---|---|
| Synonym | More Synonyms |
Uric acid-15N2 BiologicalActivity
| Description | Uric acid-15N2 is the 15N labeled Uric acid[1]. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[2][3]. |
|---|---|
| Related Catalog | Research Areas >>Inflammation/Immunology |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32(11):1839-1845. [3]. Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 202050(4):359-375. |
Chemical & Physical Properties
| Density | 1.87g/cm3 |
|---|---|
| Melting Point | >300ºC(lit.) |
| Molecular Formula | C5H4N4O3 |
| Molecular Weight | 170.09700 |
| Exact Mass | 170.02200 |
| PSA | 114.37000 |
| Index of Refraction | 1.721 |
| InChIKey | LEHOTFFKMJEONL-IOOOXAEESA-N |
| SMILES | O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
Synonyms
| Uric acid-1,3-15N2 |
| MFCD00145511 |
