Introduction：Basic information about CAS 53947-92-5|Corylin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Corylin |
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| CAS Number | 53947-92-5 | Molecular Weight | 320.339 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 527.4±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H16O4 | Melting Point | / |
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| MSDS | / | Flash Point | 193.1±23.6 °C |
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Names
| Name | 7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one |
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| Synonym | More Synonyms |
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Corylin BiologicalActivity
| Description | Corylin is a major bioactive compound isolated from Psoralea corylifolia L; antibiotic or anticancer compound.IC50 value:Target: in vitro: Corylin showed an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 1.37 uM [1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersNatural Products >>FlavonoidsResearch Areas >>Cancer |
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| References | [1]. Lee SW, et al. Phenolic compounds isolated from Psoralea corylifolia inhibit IL-6-induced STAT3 activation. Planta Med. 2012 Jun;78(9):903-6. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 527.4±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H16O4 |
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| Molecular Weight | 320.339 |
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| Flash Point | 193.1±23.6 °C |
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| Exact Mass | 320.104858 |
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| PSA | 59.67000 |
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| LogP | 4.45 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.637 |
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| InChIKey | PWAACAMQKVIVPZ-UHFFFAOYSA-N |
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| SMILES | CC1(C)C=Cc2cc(-c3coc4cc(O)ccc4c3=O)ccc2O1 |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2914400090 |
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Customs
| HS Code | 2914400090 |
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| Summary | 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
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Synonyms
| 2,2,8-trimethyl-7-hydroxychromanone |
| Corylin |
| 7-hydroxy-2,2,8-trimethyl-2,3-dihydro-4H-benzopyran-4-one |
| isowighteone |
| 2,3-dihydro-7-hydroxy-2,2,8-trimethyl-4H-benzopyran-4-one |
| 7-Hydroxy-2,2,8-trimethylchroman-4-one |
| 7-Hydroxy-2,2,8-trimethyl-4-chromanone |
| 7-HYDROXY-2,2,8-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE |
| 4H-1-Benzopyran-4-one, 3-(2,2-dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy- |
| 7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one |
