CAS 66322-34-7|Dihydroguaiaretic acid

Introduction：Basic information about CAS 66322-34-7|Dihydroguaiaretic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Dihydroguaiaretic acid BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Dihydroguaiaretic acid
CAS Number	66322-34-7	Molecular Weight	330.418
Density	1.1±0.1 g/cm3	Boiling Point	488.3±40.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₆O₄	Melting Point	/
MSDS	/	Flash Point	249.1±27.3 °C

Names

Name	4-[(2R,3S)-4-(4-Hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-met hoxyphenol
Synonym	More Synonyms

Dihydroguaiaretic acid BiologicalActivity

Description	Dihydroguaiaretic acid, is isolated from the fruits of Schisandra chinensis with an anti-cancer activty[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
In Vitro	Dihydroguaiaretic acid shows inhibitory effect on Human ovarian cancer cells and A2780 Human endometrial cancer cells Ishikawa with IC50 values of 27.17 μM and 45.46 μM, respectively[1].
References	[1]. Arch Pharm Res. 2017 Apr;40(4):500-508. doi: 10.1007/s12272-017-0902-5. Epub 2017 Feb 22.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	488.3±40.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₆O₄
Molecular Weight	330.418
Flash Point	249.1±27.3 °C
Exact Mass	330.183105
PSA	58.92000
LogP	4.33
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.564
InChIKey	ADFOLUXMYYCTRR-OKILXGFUSA-N
SMILES	COc1cc(CC(C)C(C)Cc2ccc(O)c(OC)c2)ccc1O

Safety Information

Hazard Codes	Xi

Synonyms

Tetrahydrothebaine

Dihydroguaiaretic acid

4,4'-dihydroxy-3,3'-dimethoxylignan

4,5alpha-Epoxy-3,6-dimethoxy-17-methylmorphinan

4-[(2R,3S)-4-(4-Hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-methoxyphenol

Phenol, 4-[(2R,3S)-4-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-methoxy-

meso-4,4'-dihydroxy-3,3'-dimethoxylignane

meso-dihydroguaiaretic acid

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