Introduction：Basic information about CAS 516493-93-9|Azido-PEG5-amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azido-PEG5-amine |
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| CAS Number | 516493-93-9 | Molecular Weight | 306.35900 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C12H26N4O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
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| Synonym | More Synonyms |
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Azido-PEG5-amine BiologicalActivity
| Description | Azido-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Molecular Formula | C12H26N4O5 |
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| Molecular Weight | 306.35900 |
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| Exact Mass | 306.19000 |
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| PSA | 121.92000 |
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| LogP | 0.49146 |
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| InChIKey | SVPBRIZYFJFLOL-UHFFFAOYSA-N |
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| SMILES | [N-]=[N+]=NCCOCCOCCOCCOCCOCCN |
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| Storage condition | 2-8°C |
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Synonyms
| 17-azido-3,6,9,12,15-pentaoxaheptadecanamine |
| 5-PEG amino azide |
| 17-azido-3,6,9,12,15-pentaoxa-1-heptadecylamine |
| 17-azide-3,6,9,12,15-pentaoxaheptadecan-1-amine |
| Azido-PEG5-Amine |
| 17-AZIDO-3,6,9,12,15-PENTAOXAHEPTADECAN-1-AMINE |
| 1-amino-17-azido-3,6,9,12,15-pentaoxaheptadecane |
