Introduction：Basic information about CAS 1091627-77-8|BocNH-PEG6-CH2CH2NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | BocNH-PEG6-CH2CH2NH2 |
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| CAS Number | 1091627-77-8 | Molecular Weight | 424.53000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C19H40N2O8 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | tert-butyl N-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate |
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| Synonym | More Synonyms |
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BocNH-PEG6-CH2CH2NH2 BiologicalActivity
| Description | Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Molecular Formula | C19H40N2O8 |
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| Molecular Weight | 424.53000 |
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| Exact Mass | 424.27800 |
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| PSA | 123.22000 |
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| LogP | 1.47410 |
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| InChIKey | HYSRAUNKYCBBFY-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCN |
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Synonyms
| t-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosylcarbamate |
| 22-AMINO-5,8,11,14,17,20-HEXAOXA-2-AZADOCOSANOIC ACID 1,1-DIMETHYLETHYL ESTER |
| Boc-NH-PEG6-CH2CH2NH2 |
