CAS 24782-64-7|4-CARBOXY-9-ACRIDANONE

Introduction:Basic information about CAS 24782-64-7|4-CARBOXY-9-ACRIDANONE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name4-CARBOXY-9-ACRIDANONE
CAS Number24782-64-7Molecular Weight239.22600
Density1.397g/cm3Boiling Point469.9ºC at 760 mmHg
Molecular FormulaC14H9NO3Melting Point>185 °C(dec.)
MSDS/Flash Point238ºC

Names

Name9-oxo-10H-acridine-4-carboxylic acid
SynonymMore Synonyms

4-CARBOXY-9-ACRIDANONE BiologicalActivity

DescriptionAcridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Pal C, et al. Synthesis of novel heme-interacting acridone derivatives to prevent free heme-mediated protein oxidation and degradation. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3563-7.

Chemical & Physical Properties

Density1.397g/cm3
Boiling Point469.9ºC at 760 mmHg
Melting Point>185 °C(dec.)
Molecular FormulaC14H9NO3
Molecular Weight239.22600
Flash Point238ºC
Exact Mass239.05800
PSA70.16000
LogP2.37950
Vapour Pressure1.24E-09mmHg at 25°C
Index of Refraction1.673
InChIKeyBATAOFZEDHPRTM-UHFFFAOYSA-N
SMILESO=C(O)c1cccc2c(=O)c3ccccc3[nH]c12

Safety Information

Hazard CodesXi
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
HS Code2933990090

Customs

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

9-oxo-9,10-dihydro-acridine-4-carboxylic acid
MFCD00957937
9,10-dihydro-9-oxoacridine-4-carboxylic acid
9,10-dihydro-9-oxo-4-acridinecarboxylic acid
4-Carboxyacridone
10H-acridin-9-one-4-carboxylic acid
4-Carboxy-9-acridanone
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