CAS 1093978-89-2|gamma-secretase modulator 2

Introduction：Basic information about CAS 1093978-89-2|gamma-secretase modulator 2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namegamma-secretase modulator 2
CAS Number1093978-89-2Molecular Weight514.47500
Density1.43 g/cm3Boiling Point729.8ºC at 760 mmHg
Molecular FormulaC25H22F4N6O2Melting Point/
MSDS/Flash Point395.2ºC

Names

Name6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
SynonymMore Synonyms

gamma-secretase modulator 2 BiologicalActivity

Descriptiongamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's diseaseIC50 value: Target: γ-secretaseγ-secretase modulator is modulation of the action of γ-secretase so as to Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain. γ-secretase modulator is usful in particular Alzheimer's disease.
Related CatalogSignaling Pathways >>Neuronal Signaling >>γ-secretaseSignaling Pathways >>Stem Cell/Wnt >>γ-secretaseResearch Areas >>Neurological Disease

Chemical & Physical Properties

Density1.43 g/cm3
Boiling Point729.8ºC at 760 mmHg
Molecular FormulaC25H22F4N6O2
Molecular Weight514.47500
Flash Point395.2ºC
Exact Mass514.17400
PSA78.07000
LogP4.73470
Storage condition2-8℃

Synonyms

2H-1-Benzopyran-2-carbonitrile,6-fluoro-3,4-dihydro-4-oxo
6-fluoro-3-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one
6-fluoro-3,4-dihydro-4-oxo-2H-1-benzopyran-2-carbonitrile
gamma-secretase modulator 2
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