CAS 88-10-8|Diethylcarbamic chloride

Introduction：Basic information about CAS 88-10-8|Diethylcarbamic chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	Diethylcarbamic chloride
CAS Number	88-10-8	Molecular Weight	135.592
Density	1.1±0.1 g/cm3	Boiling Point	186.0±9.0 °C at 760 mmHg
Molecular Formula	C₅H₁₀ClNO	Melting Point	−32 °C(lit.)
MSDS	ChineseUSA	Flash Point	75.0±0.0 °C
Symbol	GHS07, GHS08	Signal Word	Warning

Names

Name	Diethylcarbamyl chloride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	186.0±9.0 °C at 760 mmHg
Melting Point	−32 °C(lit.)
Molecular Formula	C₅H₁₀ClNO
Molecular Weight	135.592
Flash Point	75.0±0.0 °C
Exact Mass	135.045090
PSA	20.31000
LogP	1.30
Vapour Pressure	0.7±0.4 mmHg at 25°C
Index of Refraction	1.446
InChIKey	OFCCYDUUBNUJIB-UHFFFAOYSA-N
SMILES	CCN(CC)C(=O)Cl
Water Solubility	HYDROLYSIS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FD4025000

CHEMICAL NAME :: Carbamoyl chloride, diethyl-

CAS REGISTRY NUMBER :: 88-10-8

BEILSTEIN REFERENCE NO. :: 0506687

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C5-H10-Cl-N-O

MOLECULAR WEIGHT :: 135.61

WISWESSER LINE NOTATION :: GVN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2700 mg/kg

TOXIC EFFECTS :: Behavioral - coma Gastrointestinal - alteration in gastric secretion Blood - changes in spleen

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 159 ppm/7H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 12840 mg/kg

TOXIC EFFECTS :: Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5400 mg/kg/10D-I

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571246 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 43200 mg/kg/72W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(4),479,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993

Safety Information

Symbol	GHS07, GHS08
Signal Word	Warning
Hazard Statements	H302-H315-H319-H332-H335-H351
Precautionary Statements	P261-P281-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/22;R36/37/38;R40
Safety Phrases	S26-S36/37
RIDADR	UN 3265 8/PG 3
WGK Germany	1
RTECS	FD4025000
Packaging Group	II
Hazard Class	8
HS Code	2903199000

Customs

HS Code	2903199000
Summary	2903199000 other saturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles1

[Determination of low levels of diethylcarbamoyl chloride in air. First results after inhalation in rat (author's transl)].

Toxicol. Eur. Res. 3(5) , 223-8, (1981)

Synonyms

Carbamicchloride,diethyl

EINECS 201-798-5

MFCD00000636

diethylchloroformamide

N,N-diethylcarbamyl chloride

N,N-Diethylchloroformamide

Diethylcarbamyl chlo

diethylaminocarbonyl chloride

diethyl-carbamoylchlorid

N,N-diethylcarbamic acid chloride

diethyl-carbamicchlorid

Diethylaminoformyl chloride(D.E.C.C)

Diethylcarbamic chloride

diethylcarbamic acid chloride

Carbamic chloride, diethyl-

N,N-diethyl carbamoyl chloride

DECC

N,N-diethylaminocarbonyl chloride

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