CAS 56592-32-6|efrotomycin

Introduction:Basic information about CAS 56592-32-6|efrotomycin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Nameefrotomycin
CAS Number56592-32-6Molecular Weight1145.33000
Density/Boiling Point/
Molecular FormulaC59H88N2O20Melting Point/
MSDS/Flash Point/

Names

Name2-[2,3-dihydroxy-4-[3-hydroxy-5-(4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl)oxy-4-methoxy-6-methyloxan-2-yl]oxy-5,5-dimethyl-6-[(1E,3E)-penta-1,3-dienyl]oxan-2-yl]-N-[(2E,4E)-7-[3,4-dihydroxy-5-[(1E,3E,5E,7E)-7-hydroxy-6-methyl-7-(1-methyl-2,4-dioxopyridin
SynonymMore Synonyms

efrotomycin BiologicalActivity

DescriptionEfrotomycin is an orally active antibiotic. Efrotomycin can be isolated from the Streptomyces Lactamdurans. Efrotomycin has insignificant effect on Salmonella typhimurium quantity, duration, shedding rate, and antimicrobial susceptibility in infected pigs[1][2].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
In VivoEfrotomycin (16 mg/kg; 口服,加在饲料中; 共 56 天) 处理鼠伤寒沙门菌感染的猪,不影响脱落的菌落在定植后对抗菌药物的敏感性[1]。 Efrotomycin (16 mg/kg; 口服; 共 56 天) 处理的猪,在饲料消耗、体重增加或饲料效率方面没有明显差异[1]。
References

[1]. Wax R, et al. Efrotomycin, a new antibiotic from Streptomyces lactamdurans. J Antibiot (Tokyo). 1976 Jun;29(6):670-3.  

[2]. Jacks TM, et al. Effect of efrotomycin in feed on the quantity, duration, and prevalence of shedding and antibacterial susceptibility of Salmonella typhimurium in experimentally infected swine. Am J Vet Res. 1988 Nov;49(11):1832-5.  

Chemical & Physical Properties

Molecular FormulaC59H88N2O20
Molecular Weight1145.33000
Exact Mass1144.59000
PSA303.88000
LogP3.60900
Index of Refraction1.574
InChIKeyASOJLQIBBYOFDE-SBHXXGSWSA-N
SMILESCC=CC=CC1OC(O)(C(CC)C(=O)NCC=CC=C(C)C(OC)C(C)C2OC(C=CC=CC=C(C)C(=O)c3c(O)ccn(C)c3=O)C(O)C2O)C(O)C(OC2OC(C)C(OC3OC(C)C(OC)C(O)C3OC)C(OC)C2O)C1(C)C

Synonyms

Antibiotic FR 02A
Producil
FR 02A
efrotomycin
MK-621
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