CAS 2227-79-4|Thiobenzamide
Introduction：Basic information about CAS 2227-79-4|Thiobenzamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Thiobenzamide | ||
|---|---|---|---|
| CAS Number | 2227-79-4 | Molecular Weight | 137.202 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 245.0±23.0 °C at 760 mmHg |
| Molecular Formula | C7H7NS | Melting Point | 113-117 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 102.0±22.6 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | benzenecarbothioamide |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 245.0±23.0 °C at 760 mmHg |
| Melting Point | 113-117 °C(lit.) |
| Molecular Formula | C7H7NS |
| Molecular Weight | 137.202 |
| Flash Point | 102.0±22.6 °C |
| Exact Mass | 137.029922 |
| PSA | 58.11000 |
| LogP | 1.49 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.653 |
| InChIKey | QIOZLISABUUKJY-UHFFFAOYSA-N |
| SMILES | NC(=S)c1ccccc1 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 95 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6300 mg/kg/15W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - multiple effects Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13 gm/kg/38W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13300 mg/kg/38W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 180 umol/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 192,141,1987
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 180 umol/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 192,141,1987
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R25 |
| Safety Phrases | S45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | CV5860000 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 2930909090 |
Customs
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles28
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| Potent inhibition of alcohol self-administration in alcohol-preferring rats by a κ-opioid receptor antagonist. J. Pharmacol. Exp. Ther. 350(1) , 171-80, (2014) A substituted aryl amide derivative of 6-naltrexamine--17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-trimethylfluoro)benzamido]morphinan-hydrochloride--(compound 5), previously shown to be a... | |
| Facile synthesis of nitriles via manganese oxide promoted oxidative dehydrosulfurization of primary thioamides. Chem. Commun. (Camb.) 48(91) , 11247-9, (2012) In the presence of manganese oxides, dehydrosulfurization of various kinds of primary thioamides including aromatic, heterocyclic, and aliphatic ones efficiently proceeded to give the corresponding ni... |
Synonyms
| Benzenecarbothioamide |
| EINECS 218-765-6 |
| phenylthioamide |
| MFCD00008060 |
| Benzamide,thio |
| Benzenecarbimidothioic acid |
| aminophenylmethane-1-thione |
| Thiobenzamide |
| Benzenecarboximidothioic acid |
| Benzothioamide |
| Benzothiamide |
