CAS 722-27-0|4-Aminophenyl disulfide

Introduction：Basic information about CAS 722-27-0|4-Aminophenyl disulfide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	4-Aminophenyl disulfide
CAS Number	722-27-0	Molecular Weight	248.367
Density	1.3±0.1 g/cm3	Boiling Point	447.0±30.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₂N₂S₂	Melting Point	77-78 °C(lit.)
MSDS	USA	Flash Point	224.2±24.6 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	4,4'-Dithiodianiline
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	447.0±30.0 °C at 760 mmHg
Melting Point	77-78 °C(lit.)
Molecular Formula	C₁₂H₁₂N₂S₂
Molecular Weight	248.367
Flash Point	224.2±24.6 °C
Exact Mass	248.044189
PSA	102.64000
LogP	1.65
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.741
InChIKey	MERLDGDYUMSLAY-UHFFFAOYSA-N
SMILES	Nc1ccc(SSc2ccc(N)cc2)cc1
Stability	Stable. Incompatible with acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents. Sensitive to air.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX9580000

CHEMICAL NAME :: Aniline, p,p'-dithiodi-

CAS REGISTRY NUMBER :: 722-27-0

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H12-N2-S2

MOLECULAR WEIGHT :: 248.38

WISWESSER LINE NOTATION :: ZR DSSR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 434 mg/kg/7D-I

TOXIC EFFECTS :: Endocrine - changes in adrenal weight Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - changes in iron

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,123,1979

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	BX9580000
Hazard Class	9.0
HS Code	2930909090

Customs

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles2

Elevated glutathione accelerates oxidative damage to erythrocytes produced by aromatic disulfide.

Blood 73(1) , 312-7, (1989)

It has been shown that certain dogs have erythrocytes characterized by an inherited high concentration of reduced glutathione (GSH), five to seven times the normal level (high-GSH RBCs). We examined w...

Kinetics of polymerization of hemoglobin S modified by thiol reagents and by oxidation.

Biochim. Biophys. Acta 830(1) , 71-9, (1985)

The effects of four thiol reagents on the kinetics of polymerization of hemoglobin S have been studied in high phosphate buffer (1.8 M), in the presence (3 mM) or absence of sodium dithionite, dependi...

Synonyms

Dithioaniline

4,4'-Diaminodiphenyl disulphide

4-Aminophenyl disulfide

p-p'-Dithiodianiline

4,4'-Dithio-Aniline

4-aminophenyl

{4-[(4-Aminophenyl)dithio]phenyl}amine

4,4'-Disulfanediyldianiline

MFCD00007882

Benzenamine, 4,4'-dithiobis-

EINECS 211-961-2

4,4'-diamino diphenyl disulfide

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