Introduction：Basic information about CAS 2491-38-5|2-Bromo-4'-hydroxyacetophenone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Bromo-4'-hydroxyacetophenone |
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| CAS Number | 2491-38-5 | Molecular Weight | 215.044 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 338.7±17.0 °C at 760 mmHg |
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| Molecular Formula | C8H7BrO2 | Melting Point | 123-126°C |
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| MSDS | ChineseUSA | Flash Point | 158.6±20.9 °C |
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Names
| Name | 2-Bromo-4'-hydroxyacetophenone |
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| Synonym | More Synonyms |
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2-Bromo-4'-hydroxyacetophenone BiologicalActivity
| Description | 2-Bromo-4'-hydroxyacetophenone a PTP1B inhibitor, with a Ki of 42 μM[1]. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>PhosphataseResearch Areas >>Others |
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| Target | Ki: 42 μM (PTP1B)[1]. |
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| References | [1]. Sidhu, Alban, et al. Toward Inhibitors of Protein Tyrosine Phosphatases for Cancer Treatment. Home / Current Enzyme Inhibition, Volume 4, Number 1. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 338.7±17.0 °C at 760 mmHg |
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| Melting Point | 123-126°C |
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| Molecular Formula | C8H7BrO2 |
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| Molecular Weight | 215.044 |
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| Flash Point | 158.6±20.9 °C |
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| Exact Mass | 213.962936 |
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| PSA | 37.30000 |
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| LogP | 1.95 |
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| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
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| Index of Refraction | 1.609 |
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| InChIKey | LJYOFQHKEWTQRH-UHFFFAOYSA-N |
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| SMILES | O=C(CBr)c1ccc(O)cc1 |
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| Storage condition | -70°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AM5982000
- CHEMICAL NAME :
- Acetophenone, 2-bromo-4'-hydroxy-
- CAS REGISTRY NUMBER :
- 2491-38-5
- BEILSTEIN REFERENCE NO. :
- 1865388
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C8-H7-Br-O2
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Safety Information
| Hazard Codes | C: Corrosive; |
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| Risk Phrases | 22-36 |
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| Safety Phrases | 26 |
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| RIDADR | UN 1760 |
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| Packaging Group | III |
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| HS Code | 2914700090 |
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Customs
| HS Code | 2914700090 |
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| Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |
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Synonyms
| 4-(Bromoacetyl)phenol |
| PTP INHIBITOR I |
| 4-Hydroxyphenacyl Bromide |
| Ethanone, 2-bromo-1-(4-hydroxyphenyl)- |
| Butrol 1130 |
| p-Hydroxyphenacyl BroMide |
| 2-Bromo-1-(4-hydroxyphenyl)ethanone |
| BHAP |
| 2-Bromo-4'-Hydroxy-Acetophenone |
| 2-Bromo-4-Hydroxyacetophenone |
| MFCD00072424 |
| 4-HYDROXYPHENACYL BR |
| 2-Bromo-1-(4-hydroxyphenyl)ethanone p-Hydroxyphenacyl bromide |
| BUSAN1130 |
| 2-Bromo-4’-hydroxyacetophenone |
| BUSAN90 |
| BROMOHYDROXYACETOPHENONE |
| 1-(4-hydroxyphenyl)-2-bromoethanone |
| EINECS 219-655-0 |
