CAS 1086-80-2|LUMICHROME
| Common Name | LUMICHROME | ||
|---|---|---|---|
| CAS Number | 1086-80-2 | Molecular Weight | 242.23300 |
| Density | 1.388g/cm3 | Boiling Point | / |
| Molecular Formula | C12H10N4O2 | Melting Point | 300 °C |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | lumichrome |
|---|---|
| Synonym | More Synonyms |
LUMICHROME BiologicalActivity
| Description | Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
| Target | Human Endogenous Metabolite |
| References | [1]. Bergh VJ, et al. Influence of formulation on photoinactivation of bacteria by lumichrome. Pharmazie. 2015;70(9):574-580. [2]. Chantarawong W, et al. Lumichrome Inhibits Human Lung Cancer Cell Growth and Induces Apoptosis via a p53-Dependent Mechanism. Nutr Cancer. 2019;71(8):1390-1402. |
Chemical & Physical Properties
| Density | 1.388g/cm3 |
|---|---|
| Melting Point | 300 °C |
| Molecular Formula | C12H10N4O2 |
| Molecular Weight | 242.23300 |
| Exact Mass | 242.08000 |
| PSA | 91.50000 |
| LogP | 0.77640 |
| Index of Refraction | 1.66 |
| InChIKey | ZJTJUVIJVLLGSP-UHFFFAOYSA-N |
| SMILES | Cc1cc2nc3[nH]c(=O)[nH]c(=O)c3nc2cc1C |
| Stability | Stable. Incompatible with strong oxidizing agents. Combustible. |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles32
More Articles| Enhanced Indirect Photochemical Transformation of Histidine and Histamine through Association with Chromophoric Dissolved Organic Matter. Environ. Sci. Technol. 49 , 5511-9, (2015) Photochemical transformations greatly affect the stability and fate of amino acids (AAs) in sunlit aquatic ecosystems. Whereas the direct phototransformation of dissolved AAs is well investigated, the... | |
| The B vitamins nicotinamide (B3) and riboflavin (B2) stimulate metamorphosis in larvae of the deposit-feeding polychaete Capitella teleta: implications for a sensory ligand-gated ion channel. PLoS ONE 9(11) , e109535, (2014) Marine sediments can contain B vitamins, presumably incorporated from settled, decaying phytoplankton and microorganisms associated with decomposition. Because B vitamins may be advantageous for the e... | |
| Molecular and functional characterization of riboflavin specific transport system in rat brain capillary endothelial cells. Brain Res. 1468 , 1-10, (2012) Riboflavin is an important water soluble vitamin (B2) required for metabolic reactions, normal cellular growth, differentiation and function. Mammalian brain cells cannot synthesize riboflavin and mus... |
Synonyms
| MFCD00005021 |
| 7,8-Dimethylalloxazine |
| LUM |
| flavins |
| 7,8-dimethyl-1H-benzo[g]pteridine-2,4-dione |
| 6,7-DIMETHYLALLOXAZINE |
| EINECS 214-120-8 |
| Benzo[g]pteridine-2,4(1H,3H)-dione,7,8-dimethyl |
| 7,8-dimethyl-benzo[g]pteridine-2,4(1H,3H)-dione |
