Introduction：Basic information about CAS 108657-10-9|Eupalinolide K, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Eupalinolide K |
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| CAS Number | 108657-10-9 | Molecular Weight | 362.417 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 574.4±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H26O6 | Melting Point | / |
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| MSDS | / | Flash Point | 201.5±23.6 °C |
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Names
| Name | (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone |
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| Synonym | More Synonyms |
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Eupalinolide K BiologicalActivity
| Description | Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1]. |
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| Related Catalog | Signaling Pathways >>Stem Cell/Wnt >>STATSignaling Pathways >>JAK/STAT Signaling >>STATResearch Areas >>Others |
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| Target | STAT3 |
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| References | [1]. Yang B, , et al. Precise discovery of a STAT3 inhibitor from Eupatorium lindleyanum and evaluation of its activity of anti-triple-negative breast cancer. Nat Prod Res. 2019 Feb;33(4):477-485. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 574.4±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H26O6 |
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| Molecular Weight | 362.417 |
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| Flash Point | 201.5±23.6 °C |
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| Exact Mass | 362.172943 |
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| PSA | 93.06000 |
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| LogP | 2.29 |
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| Vapour Pressure | 0.0±3.6 mmHg at 25°C |
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| Index of Refraction | 1.557 |
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| InChIKey | APOGLVUGPAVNAP-GIDICUODSA-N |
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| SMILES | C=C1C(=O)OC2C=C(C)C(O)CC=C(C)CC(OC(=O)C(C)=CCO)C12 |
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Synonyms
| 2-Butenoic acid, 4-hydroxy-2-methyl-, (3aR,4S,6Z,9S,10Z,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2E)- |
| 3β-hydroxy-8β-[4'-hydroxytigloyloxy]costunolide |
| (2E)-4-hydroxy-2-methylbut-2-enoic acid (3aR,4R,6E,9S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester |
| (3aR,4S,6Z,9S,10Z,11aR)-9-Hydroxy-6,10-dimethyl-3-methylene-2-oxo-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-4-yl (2E)-4-hydroxy-2-methyl-2-butenoate |
| eupalinolide K |
