Introduction:Basic information about CAS 2140-71-8|2'-O-Methylguanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-O-Methylguanosine |
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| CAS Number | 2140-71-8 | Molecular Weight | 297.267 |
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| Density | 2.0±0.1 g/cm3 | Boiling Point | 711.7ºC at 760 mmHg |
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| Molecular Formula | C11H15N5O5 | Melting Point | 218-220ºC |
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| MSDS | / | Flash Point | 384.2ºC |
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Names
| Name | 2'-O-methylguanosine |
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| Synonym | More Synonyms |
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2'-O-Methylguanosine BiologicalActivity
| Description | 2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells[1][2]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Metabolic Disease |
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| References | [1]. B C Persson, et al. The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity. Nucleic Acids Res. 1997 Oct 15;25(20):4093-7. [2]. T Mori, et al. Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line. Biochem Biophys Res Commun. 1998 Oct 20;251(2):416-22. |
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Chemical & Physical Properties
| Density | 2.0±0.1 g/cm3 |
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| Boiling Point | 711.7ºC at 760 mmHg |
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| Melting Point | 218-220ºC |
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| Molecular Formula | C11H15N5O5 |
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| Molecular Weight | 297.267 |
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| Flash Point | 384.2ºC |
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| Exact Mass | 297.107330 |
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| PSA | 148.51000 |
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| LogP | -0.36 |
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| Vapour Pressure | 2.93E-21mmHg at 25°C |
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| Index of Refraction | 1.829 |
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| Storage condition | Refrigerator |
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | 36/37/38 |
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| Safety Phrases | 26-36 |
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| HS Code | 2934999090 |
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Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Guanosine, 2'-O-methyl- |
| 2'-methylguanosine |
| Gm19 |
| 2'-O-(TERT-BUTYLDIMETHYLSILYL)PACLITAXEL |
| UNII-W722H4PA1S |
| 2'-O-Methylguanosine |
| Guanosine,2'-O-methyl |
| 2'-O-Methyl Guanosine |
| 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-purin-6-one |
| MFCD00057053 |
| O2'-methyl-guanosine |
| 2'-O-methyl-guanosine |
| 2’-OMeGuanosine |
| 2'-O-Methylguanosine Hydrate |