CAS 2140-71-8|2'-O-Methylguanosine

Introduction:Basic information about CAS 2140-71-8|2'-O-Methylguanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2'-O-Methylguanosine
CAS Number2140-71-8Molecular Weight297.267
Density2.0±0.1 g/cm3Boiling Point711.7ºC at 760 mmHg
Molecular FormulaC11H15N5O5Melting Point218-220ºC
MSDS/Flash Point384.2ºC

Names

Name2'-O-methylguanosine
SynonymMore Synonyms

2'-O-Methylguanosine BiologicalActivity

Description2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells[1][2].
Related CatalogSignaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Metabolic Disease
References

[1]. B C Persson, et al. The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity. Nucleic Acids Res. 1997 Oct 15;25(20):4093-7.

[2]. T Mori, et al. Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line. Biochem Biophys Res Commun. 1998 Oct 20;251(2):416-22.

Chemical & Physical Properties

Density2.0±0.1 g/cm3
Boiling Point711.7ºC at 760 mmHg
Melting Point218-220ºC
Molecular FormulaC11H15N5O5
Molecular Weight297.267
Flash Point384.2ºC
Exact Mass297.107330
PSA148.51000
LogP-0.36
Vapour Pressure2.93E-21mmHg at 25°C
Index of Refraction1.829
Storage conditionRefrigerator

Safety Information

Hazard CodesXi
Risk Phrases36/37/38
Safety Phrases26-36
HS Code2934999090

Customs

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Guanosine, 2'-O-methyl-
2'-methylguanosine
Gm19
2'-O-(TERT-BUTYLDIMETHYLSILYL)PACLITAXEL
UNII-W722H4PA1S
2'-O-Methylguanosine
Guanosine,2'-O-methyl
2'-O-Methyl Guanosine
2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-purin-6-one
MFCD00057053
O2'-methyl-guanosine
2'-O-methyl-guanosine
2’-OMeGuanosine
2'-O-Methylguanosine Hydrate
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