CAS 32886-97-8|PIVMECILLINAM
| Common Name | PIVMECILLINAM | ||
|---|---|---|---|
| CAS Number | 32886-97-8 | Molecular Weight | 439.569 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 581.0±60.0 °C at 760 mmHg |
| Molecular Formula | C21H33N3O5S | Melting Point | 118-119ºC |
| MSDS | ChineseUSA | Flash Point | 305.2±32.9 °C |
Names
| Name | pivmecillinam |
|---|---|
| Synonym | More Synonyms |
PIVMECILLINAM BiologicalActivity
| Description | Pivmecillinam (FL-1039) is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
| References | [1]. Nicolle LE. Pivmecillinam in the treatment of urinary tract infections. J Antimicrob Chemother. 2000 Aug;46 Suppl A:35-39. [2]. Graninger W. Pivmecillinam--therapy of choice for lower urinary tract infection. Int J Antimicrob Agents. 2003 Oct;22 Suppl 2:73-8. [3]. Holme E, et al. Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. Lancet. 1989 Aug 26;2(8661):469-73. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 581.0±60.0 °C at 760 mmHg |
| Melting Point | 118-119ºC |
| Molecular Formula | C21H33N3O5S |
| Molecular Weight | 439.569 |
| Flash Point | 305.2±32.9 °C |
| Exact Mass | 439.214081 |
| PSA | 113.81000 |
| LogP | 2.97 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.604 |
| InChIKey | NPGNOVNWUSPMDP-HLLBOEOZSA-N |
| SMILES | CC(C)(C)C(=O)OCOC(=O)C1N2C(=O)C(N=CN3CCCCCC3)C2SC1(C)C |
| Storage condition | 2-8℃ |
Safety Information
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-37/39 |
| RIDADR | NONH for all modes of transport |
| RTECS | XI0185000 |
Articles28
More Articles| Use of antibiotics in nursing homes--surveillance with different methods. Tidsskr. Nor. Laegeforen. 133(19) , 2052-6, (2013) Residents in nursing homes have a heightened risk of developing infections that should be treated with antibiotics. Inappropriate use of antibiotics may generate drug-related problems and increase res... | |
| New media for the semiselective isolation and enumeration of Xanthomonas campestris pv. mangiferaeindicae, the causal agent of mango bacterial black spot. J. Appl. Microbiol. 99(4) , 803-15, (2005) Mango bacterial black spot, caused by Xanthomonas campestris pv. mangiferaeindicae, is a potentially severe disease in several tropical and subtropical areas. Data describing the life cycle of the pat... | |
| Oral treatment options for ambulatory patients with urinary tract infections caused by extended-spectrum-beta-lactamase-producing Escherichia coli. Antimicrob. Agents Chemother. 54 , 4006-8, (2010) An increase in extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli has been observed in outpatient settings. Consequently, 100 ESBL-positive E. coli isolates from ambulatory patients wi... |
Synonyms
| Melysin |
| Hydroxymethyl (2S,5R,6R)-6-(((hexahydro-1H-azepin-1-yl)methylene)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Pivalate (Ester) |
| PIVMECILLINAM |
| 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(1E)-(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S,5R,6R)- |
| [(2,2-Dimethylpropanoyl)oxy]methyl (2S,5R,6R)-6-[(azepan-1-ylmethylene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Pivamdinocillin |
| [2S-(2a,5a,6b)]-6-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester |
| [(2,2-dimethylpropanoyl)oxy]methyl (2S,5R,6R)-6-[(azepan-1-ylmethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| [(2,2-Dimethylpropanoyl)oxy]methyl (2S,5R,6R)-6-{(E)-[(E)-1-azepanylmethylene]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S,5R,6R)- |
| AMDINOCILLIN PIVOXIL |
| Coactabs |
