CAS 514-10-3|abietic acid

Introduction:Basic information about CAS 514-10-3|abietic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Nameabietic acid
CAS Number514-10-3Molecular Weight302.451
Density1.1±0.1 g/cm3Boiling Point439.5±44.0 °C at 760 mmHg
Molecular FormulaC20H30O2Melting Point139-142 °C(lit.)
MSDS/Flash Point208.1±23.1 °C

Names

Nameabietic acid
SynonymMore Synonyms

abietic acid BiologicalActivity

DescriptionAbietic acid, a diterpene isolated from Pimenta racemosa var. grissea, possesses antiproliferative, antibacterial, and anti-obesity properties. Abietic acid inhibits lipoxygenase activity for allergy treatment[1][2].
Related CatalogResearch Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyResearch Areas >>Metabolic Disease
References

[1]. Ulusu NN, et al. Abietic acid inhibits lipoxygenase activity. Phytother Res. 2002 Feb;16(1):88-90.

[2]. Fernández MA, et al. Anti-inflammatory activity of abietic acid, a diterpene isolated from Pimenta racemosa var. grissea. J Pharm Pharmacol. 2001 Jun;53(6):867-72.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point439.5±44.0 °C at 760 mmHg
Melting Point139-142 °C(lit.)
Molecular FormulaC20H30O2
Molecular Weight302.451
Flash Point208.1±23.1 °C
Exact Mass302.224579
PSA37.30000
LogP6.51
Vapour Pressure0.0±2.3 mmHg at 25°C
Index of Refraction1.542
InChIKeyRSWGJHLUYNHPMX-ONCXSQPRSA-N
SMILESCC(C)C1=CC2=CCC3C(C)(C(=O)O)CCCC3(C)C2CC1
StabilityStable. Combustible. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP8580000
CHEMICAL NAME :
Podocarpa-7,13-dien-15-oic acid, 13-isopropyl-
CAS REGISTRY NUMBER :
514-10-3
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H30-O2
MOLECULAR WEIGHT :
302.50
WISWESSER LINE NOTATION :
L B666 EU GUTJ A1 EY1&1 KVQ K1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02819 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2302 No. of Facilities: 5012 (estimated) No. of Industries: 34 No. of Occupations: 47 No. of Employees: 31118 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2302 No. of Facilities: 171 (estimated) No. of Industries: 5 No. of Occupations: 11 No. of Employees: 3942 (estimated) No. of Female Employees: 646 (estimated)

Safety Information

Hazard CodesXi:Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRUN 3077 9/PG 3
WGK Germany3
RTECSTP8580000
Hazard Class9.0
HS Code2916209090

Customs

HS Code2916209090
Summary2916209090 other cyclanic, cyclenic or cyclotherpenic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Synonyms

Abietic acid
EINECS 208-178-3
7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydrophenanthrene-1-carboxylic acid
7,13-Abietadien-18-oic acid
1,1-Dimethyl-7-isopropyl-1,2,3,4-tetrahydro-phenanthren
Sylvic Acid
abieta-7,13-diene-18-oic acid
MFCD03423567
simonellite
abieta-7,13-dien-18-oic acid
7-Isopropyl-1,1-dimethyl-1,2,3,4-tetrahydro-phenanthren
7-isopropyl-1,1-dimethyl-1,2,3,4-tetrahydro-phenanthrene
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