CAS 517-28-2|Hematoxylin

Introduction:Basic information about CAS 517-28-2|Hematoxylin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameHematoxylin
CAS Number517-28-2Molecular Weight302.279
Density1.7±0.1 g/cm3Boiling Point579.9±50.0 °C at 760 mmHg
Molecular FormulaC16H14O6Melting Point200 °C (dec.)(lit.)
MSDSChineseUSAFlash Point304.5±30.1 °C
Symbol
GHS07
Signal WordWarning

Names

Name(+)-haematoxylin
SynonymMore Synonyms

Hematoxylin BiologicalActivity

DescriptionHematoxylin is a natural product.
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>OthersNatural Products >>Phenols
References

[1]. EF Kingston, et al. Vascular invasion is underrecognized in colorectal cancer using conventional hematoxylin and eosin staining. 《Diseases of the Colon & Rectum》, 2007, 50(11):1867-1872

[2]. JE Grilley-Olson, et al. Validation of interobserver agreement in lung cancer assessment: hematoxylin-eosin diagnostic reproducibility for non-small cell lung cancer: the 2004 World Health Organization classification and therapeutically relevant subsets.

[3]. HR Zare, et al. Simultaneous determination of ascorbic acid, adrenaline and uric acid at a hematoxylin multi-wall carbon nanotube modified glassy carbon electrode. Sensors & Actuators B Chemical, 2010, 143(2):666-672

Chemical & Physical Properties

Density1.7±0.1 g/cm3
Boiling Point579.9±50.0 °C at 760 mmHg
Melting Point200 °C (dec.)(lit.)
Molecular FormulaC16H14O6
Molecular Weight302.279
Flash Point304.5±30.1 °C
Exact Mass302.079041
PSA110.38000
LogP0.51
Vapour Pressure0.0±1.7 mmHg at 25°C
Index of Refraction1.810
InChIKeyWZUVPPKBWHMQCE-UHFFFAOYSA-N
SMILESOc1cc2c(cc1O)C1c3ccc(O)c(O)c3OCC1(O)C2
Storage conditionStore at RT.
StabilityStability Stable, but may discolour on exposure to light. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MH7875000
CHEMICAL NAME :
Hematoxylin
CAS REGISTRY NUMBER :
517-28-2
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C16-H14-O6
MOLECULAR WEIGHT :
302.30
WISWESSER LINE NOTATION :
T C6 B566 LO&TT&J EQ FQ JQ NQ OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg/26W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease
REFERENCE :
GASTAB Gastroenterology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1943- Volume(issue)/page/year: 23,1,1953 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80980 No. of Facilities: 667 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 3015 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80980 No. of Facilities: 1405 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 24188 (estimated) No. of Female Employees: 20340 (estimated)

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH302-H315-H319-H335
Precautionary StatementsP301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi:Irritant
Risk PhrasesR36/37/38
Safety Phrases26-36
RIDADRNONH for all modes of transport
WGK Germany2
RTECSMH7875000
HS Code3302101000

Customs

HS Code2906299090
Summary2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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Synonyms

Hematoxylin Hydrate
MFCD00005394
HAEMATOXYLIN(RG)
bematoxylin
Hematoxylin
Natural Black 1
Natural Black 1 Hydrate
Haematoxylin
Homaeoxylin
hydroxybrazilin
EINECS 208-237-3
h(a)ematine
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