CAS 517-28-2|Hematoxylin
| Common Name | Hematoxylin | ||
|---|---|---|---|
| CAS Number | 517-28-2 | Molecular Weight | 302.279 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 579.9±50.0 °C at 760 mmHg |
| Molecular Formula | C16H14O6 | Melting Point | 200 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 304.5±30.1 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | (+)-haematoxylin |
|---|---|
| Synonym | More Synonyms |
Hematoxylin BiologicalActivity
| Description | Hematoxylin is a natural product. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>OthersNatural Products >>Phenols |
| References | [1]. EF Kingston, et al. Vascular invasion is underrecognized in colorectal cancer using conventional hematoxylin and eosin staining. 《Diseases of the Colon & Rectum》, 2007, 50(11):1867-1872 [2]. JE Grilley-Olson, et al. Validation of interobserver agreement in lung cancer assessment: hematoxylin-eosin diagnostic reproducibility for non-small cell lung cancer: the 2004 World Health Organization classification and therapeutically relevant subsets. [3]. HR Zare, et al. Simultaneous determination of ascorbic acid, adrenaline and uric acid at a hematoxylin multi-wall carbon nanotube modified glassy carbon electrode. Sensors & Actuators B Chemical, 2010, 143(2):666-672 |
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 579.9±50.0 °C at 760 mmHg |
| Melting Point | 200 °C (dec.)(lit.) |
| Molecular Formula | C16H14O6 |
| Molecular Weight | 302.279 |
| Flash Point | 304.5±30.1 °C |
| Exact Mass | 302.079041 |
| PSA | 110.38000 |
| LogP | 0.51 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.810 |
| InChIKey | WZUVPPKBWHMQCE-UHFFFAOYSA-N |
| SMILES | Oc1cc2c(cc1O)C1c3ccc(O)c(O)c3OCC1(O)C2 |
| Storage condition | Store at RT. |
| Stability | Stability Stable, but may discolour on exposure to light. Incompatible with strong oxidizing agents. |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg/26W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease
- REFERENCE :
- GASTAB Gastroenterology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1943- Volume(issue)/page/year: 23,1,1953 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80980 No. of Facilities: 667 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 3015 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80980 No. of Facilities: 1405 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 24188 (estimated) No. of Female Employees: 20340 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P301 + P312 + P330-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | MH7875000 |
| HS Code | 3302101000 |
Customs
| HS Code | 2906299090 |
|---|---|
| Summary | 2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
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Synonyms
| Hematoxylin Hydrate |
| MFCD00005394 |
| HAEMATOXYLIN(RG) |
| bematoxylin |
| Hematoxylin |
| Natural Black 1 |
| Natural Black 1 Hydrate |
| Haematoxylin |
| Homaeoxylin |
| hydroxybrazilin |
| EINECS 208-237-3 |
| h(a)ematine |
