CAS 3226-65-1|H-Met(O)-OH
| Common Name | H-Met(O)-OH | ||
|---|---|---|---|
| CAS Number | 3226-65-1 | Molecular Weight | 165.211 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 434.3±40.0 °C at 760 mmHg |
| Molecular Formula | C5H11NO3S | Melting Point | 234-235ºC |
| MSDS | ChineseUSA | Flash Point | 216.4±27.3 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | L-methionine S-oxide |
|---|---|
| Synonym | More Synonyms |
H-Met(O)-OH BiologicalActivity
| Description | L-Methionine sulfoxide (H-Met(O)-OH), a metabolite of Methionine, induces M1/classical macrophage polarization, and modulates oxidative stress and purinergic signaling parameters[1]. |
|---|---|
| Related Catalog | Research Areas >>Metabolic Disease |
| References | [1]. Dos Santos LM, et al. Methionine and methionine sulfoxide treatment induces M1/classical macrophage polarization and modulates oxidative stress and purinergic signaling parameters. Mol Cell Biochem. 2017 Jan;424(1-2):69-78. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 434.3±40.0 °C at 760 mmHg |
| Melting Point | 234-235ºC |
| Molecular Formula | C5H11NO3S |
| Molecular Weight | 165.211 |
| Flash Point | 216.4±27.3 °C |
| Exact Mass | 165.045959 |
| PSA | 99.60000 |
| LogP | -1.62 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.570 |
| InChIKey | QEFRNWWLZKMPFJ-YGVKFDHGSA-N |
| SMILES | CS(=O)CCC(N)C(=O)O |
| Storage condition | 2-8°C |
| Stability | Temperature Sensitive, Hygroscopic |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xn |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2930909090 |
Customs
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles36
More Articles| Copper(II) complexes of neurokinin A with point mutation (S5A) and products of copper-catalyzed oxidation; role of serine residue in peptides containing neurokinin A sequence. J. Inorg. Biochem. 121 , 1-9, (2013) A potentiometric, spectroscopic (UV-visible, CD and EPR) and electrospray ionization mass spectrometric (ESI-MS) study of Cu(II) binding to the neurokinin A with point mutation (S5A) (ANKA), His-Lys-T... | |
| Changes of metabolic profiles in an oral squamous cell carcinoma cell line induced by eugenol. In Vivo 27(2) , 233-43, (2013) We have recently reported that eugenol exerted indiscriminate cytotoxicity towards normal oral cells and oral squamous cell carcinoma (OSCC) cell lines without induction of apoptosis markers. In order... | |
| Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A. Cell Death Dis. 5 , e1490, (2014) Methionine sulfoxide reductase A (MSRA) protects proteins from oxidation, and also helps remove reactive oxygen species (ROS) by recovering antioxidant enzymes inactivated by oxidation. Although its f... |
Synonyms
| Butanoic acid, 2-amino-4-(methylsulfinyl)-, (2S)- |
| EINECS 221-758-0 |
| (2S)-2-Amino-4-(methylsulfinyl)butanoic acid |
| (3-Amino-3-carboxypropyl)(methyl)sulfoniumolate |
| 2-Amino-4-(methylsulfinyl)butanoic acid |
| UNII:XN1XVI4B2C |
| MFCD00063093 |
| L-methionine S-oxide |
| L-2-Amino-4-(methylsulfinyl)butanoic acid |
| Butanoic acid, 2-amino-4-(methylsulfinyl)- |
| sulfonium, (3-amino-3-carboxypropyl)hydroxymethyl-, inner salt |
| UNII:O74B4F6OYL |
| L-Methionine Sulfoxide |
| H-Met(O)-OH |
