CAS 119-90-4|3,3'-Dimethoxybiphenyl-4,4'-diamine
Introduction：Basic information about CAS 119-90-4|3,3'-Dimethoxybiphenyl-4,4'-diamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3,3'-Dimethoxybiphenyl-4,4'-diamine | ||
|---|---|---|---|
| CAS Number | 119-90-4 | Molecular Weight | 244.289 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 391.3±37.0 °C at 760 mmHg |
| Molecular Formula | C14H16N2O2 | Melting Point | 137-138 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 206.1±0.0 °C |
| Symbol | GHS07, GHS08 | Signal Word | Danger |
Names
| Name | 3,3'-dimethoxybenzidine |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 391.3±37.0 °C at 760 mmHg |
| Melting Point | 137-138 °C(lit.) |
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.289 |
| Flash Point | 206.1±0.0 °C |
| Exact Mass | 244.121185 |
| PSA | 70.50000 |
| LogP | 1.58 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.619 |
| InChIKey | JRBJSXQPQWSCCF-UHFFFAOYSA-N |
| SMILES | COc1cc(-c2ccc(N)c(OC)c2)ccc1N |
| Water Solubility | H2O: slightly soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1920 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 gm/kg/56W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 588 gm/kg/70W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TYPE OF TEST :
- Cytogenetic analysis
MUTATION DATA - TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - dog Cells - not otherwise specified
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,1893,1984 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,41,1974 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,198,1987 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,198,1987 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-SWEDEN;Carcinogen JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO o-DIANISIDINE-BASED DYES-air:CA lowest feasible conc. REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80274 No. of Facilities: 49 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 122 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80274 No. of Facilities: 92 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 2481 (estimated) No. of Female Employees: 866 (estimated)
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - dog Cells - not otherwise specified
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,1893,1984 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,41,1974 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,198,1987 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,198,1987 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-SWEDEN;Carcinogen JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO o-DIANISIDINE-BASED DYES-air:CA lowest feasible conc. REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80274 No. of Facilities: 49 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 122 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80274 No. of Facilities: 92 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 2481 (estimated) No. of Female Employees: 866 (estimated)
Safety Information
| Symbol | GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H350 |
| Precautionary Statements | P201-P308 + P313 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T:Toxic; |
| Risk Phrases | R45;R22 |
| Safety Phrases | S53-S45 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | DD0875000 |
| Packaging Group | II |
| Hazard Class | 6.1(a) |
| HS Code | 2922299090 |
Customs
| HS Code | 2922299090 |
|---|---|
| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| [1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy- |
| 3,3'-Dimethoxy-4,4'-diaminodiphenyl |
| 3,3'-Dimethoxybenzidine |
| 3,3‘-Dimethoxybenzidine |
| 3,3'-Dimethoxy-4,4'-biphenyldiamine |
| 4,4'-Diamino-3,3'-dimethoxybiphenyl |
| EINECS 204-355-4 |
| 3,3'-Dimethoxy-[1,1'-biphenyl]-4,4'-diamine |
| 3,3'-Dimethoxybiphenyl-4,4'-diamine |
| Fast Blue B |
| 3,3-Dimethoxybenzidine |
| MFCD00008372 |
| o-dianisidine |
| 4-(4-amino-3-methoxyphenyl)-2-methoxyaniline |
| 3,3′-Dimethoxybenzidine |
