Introduction：Basic information about CAS 109792-60-1|Boc-DADdec, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Boc-DADdec |
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| CAS Number | 109792-60-1 | Molecular Weight | 300.48000 |
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| Density | 0.924g/cm3 | Boiling Point | 409.2ºC at 760mmHg |
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| Molecular Formula | C17H36N2O2 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 201.3ºC |
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Names
| Name | 1-boc-1,12-diaminododecane |
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| Synonym | More Synonyms |
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Boc-DADdec BiologicalActivity
| Description | Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Density | 0.924g/cm3 |
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| Boiling Point | 409.2ºC at 760mmHg |
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| Molecular Formula | C17H36N2O2 |
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| Molecular Weight | 300.48000 |
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| Flash Point | 201.3ºC |
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| Exact Mass | 300.27800 |
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| PSA | 64.35000 |
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| LogP | 5.46200 |
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| Vapour Pressure | 6.61E-07mmHg at 25°C |
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| Index of Refraction | 1.463 |
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| InChIKey | ZFSCBYAYUUFEPJ-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)NCCCCCCCCCCCCN |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi: Irritant; |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2924199090 |
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Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Boc-DADdec |
| TERT-BUTYL 12-AMINODODECYLCARBAMATE |
| N-Boc-1,12-dodecanediamine |
| N-t-Butyloxycarbonyl-1,12-diaminododecane |
| N-tert-butoxycarbonyl-1,12-diaminododecane |
| 1,12-Diaminododecane,N-BOC protected |
| tert-butyl 2,13-diaMinotridecanoate |
| mono-tert-butoxycarbonyl-1,12-diaminododecane |
