CAS 23445-00-3|Swertianolin

Introduction：Basic information about CAS 23445-00-3|Swertianolin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Swertianolin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Synonyms

Common Name	Swertianolin
CAS Number	23445-00-3	Molecular Weight	436.366
Density	1.7±0.1 g/cm3	Boiling Point	806.3±65.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₀O₁₁	Melting Point	/
MSDS	/	Flash Point	287.7±27.8 °C

Names

Name	swertianolin
Synonym	More Synonyms

Swertianolin BiologicalActivity

Description	Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity[1][2].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>HBVResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Neuronal Signaling >>AChESignaling Pathways >>Anti-infection >>Bacterial
References	[1]. Urbain A, et al. Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors. Planta Med. 2004 Oct;70(10):1011-4. [2]. Xiu-Qiao Zhang, et al. Anti-HBV Activities of Xanthones From Swertia Punicea Hemsl. N A J Med Sci. 2014;7(2):72-74.

Description

Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity[1][2].

Related Catalog

Research Areas >>InfectionSignaling Pathways >>Anti-infection >>HBVResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Neuronal Signaling >>AChESignaling Pathways >>Anti-infection >>Bacterial

References

[1]. Urbain A, et al. Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors. Planta Med. 2004 Oct;70(10):1011-4.

[2]. Xiu-Qiao Zhang, et al. Anti-HBV Activities of Xanthones From Swertia Punicea Hemsl. N A J Med Sci. 2014;7(2):72-74.

Chemical & Physical Properties

Density	1.7±0.1 g/cm3
Boiling Point	806.3±65.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₀O₁₁
Molecular Weight	436.366
Flash Point	287.7±27.8 °C
Exact Mass	436.100555
PSA	179.28000
LogP	-1.13
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.705
InChIKey	XMVBNLMKPMPWAX-UHFFFAOYSA-N
SMILES	COc1cc(O)c2c(=O)c3c(OC4OC(CO)C(O)C(O)C4O)ccc(O)c3oc2c1
Storage condition	2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZD6057000

CHEMICAL NAME :: Xanthen-9-one, 5,8-dihydroxy-1-(beta-D-glucopyranosyloxy)-3-methoxy-

CAS REGISTRY NUMBER :: 23445-00-3

LAST UPDATED :: 199503

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H20-O11

MOLECULAR WEIGHT :: 436.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 150,141,1985

Synonyms

5,8-Dihydroxy-3-methoxy-9-oxo-9H-xanthen-1-yl β-D-glucopyranoside

Sw-bromoacetophenone semicarbazone

2-bromo-1-phenyl-ethanone semicarbazone

bellidifolin 8-O-glucopyranoside

9H-Xanthen-9-one, 1-(β-D-glucopyranosyloxy)-5,8-dihydroxy-3-methoxy-

2-Brom-1-phenyl-aethanon-semicarbazon

SWERTIANOLIN

phenacyl bromide semicarbazone

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