Introduction：Basic information about CAS 56282-36-1|Thiol-C2-PEG2-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Thiol-C2-PEG2-OH |
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| CAS Number | 56282-36-1 | Molecular Weight | 166.23900 |
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| Density | 1.094g/cm3 | Boiling Point | 270.3ºC at 760 mmHg |
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| Molecular Formula | C6H14O3S | Melting Point | / |
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| MSDS | / | Flash Point | 117.3ºC |
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Names
| Name | 3,6-Dioxa-8-mercaptooctan-1-ol |
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| Synonym | More Synonyms |
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Thiol-C2-PEG2-OH BiologicalActivity
| Description | Thiol-C2-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Density | 1.094g/cm3 |
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| Boiling Point | 270.3ºC at 760 mmHg |
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| Molecular Formula | C6H14O3S |
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| Molecular Weight | 166.23900 |
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| Flash Point | 117.3ºC |
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| Exact Mass | 166.06600 |
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| PSA | 77.49000 |
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| Index of Refraction | 1.475 |
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| InChIKey | KXSLUQUKENLMJW-UHFFFAOYSA-N |
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| SMILES | OCCOCCOCCS |
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Synonyms
| 2-[2-(2-sulfanylethoxy)ethoxy]ethanol |
