Introduction：Basic information about CAS 2385-63-9|Liensinine perchlorate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Liensinine perchlorate |
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| CAS Number | 2385-63-9 | Molecular Weight | 711.198 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C37H43ClN2O10 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Liensinine Perchlorate |
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| Synonym | More Synonyms |
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Liensinine perchlorate BiologicalActivity
| Description | Liensinine Perchlorate is a constituent of Nelumbo nucifera Gaertn, with ani-hypertension and anti-cancer activities. Liensinine Perchlorate induces colorectal cancer (CRC) cell apoptosis[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>Inflammation/Immunology |
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| Target | IC50: apoptosis[1] |
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| In Vitro | Liensinine Perchlorate is found to induce apoptosis and exert a significant inhibitory effect on the proliferation and colony-forming ability of CRC cells in a dose-dependent manner without any observed cytotoxicity on normal colorectal epithelial cells[1]. |
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| References | [1]. Liensinine perchlorate inhibits colorectal cancer tumorigenesis by inducing mitochondrial dysfunction and apoptosis |
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Chemical & Physical Properties
| Molecular Formula | C37H43ClN2O10 |
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| Molecular Weight | 711.198 |
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| Exact Mass | 710.260620 |
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| PSA | 155.30000 |
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| LogP | 6.49140 |
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| InChIKey | SBJXHMBOBQYZFA-AQDPCYHDSA-N |
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| SMILES | COc1cc2c(cc1OC)C(Cc1ccc(O)c(Oc3cc4c(cc3OC)CCN(C)C4Cc3ccc(O)cc3)c1)N(C)CC2.[O-][Cl+3]([O-])([O-])O |
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Synonyms
| Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinyl]oxy]-, perchlorate (1:1) (salt) |
| 4-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-2-{[(1R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinyl]oxy}phenol perchlorate (1:1) |
