CAS 1249-81-6|Cholest-5-ene-3-thiol,(3b)-
| Common Name | Cholest-5-ene-3-thiol,(3b)- | ||
|---|---|---|---|
| CAS Number | 1249-81-6 | Molecular Weight | 402.71900 |
| Density | 0.98g/cm3 | Boiling Point | 482.4ºC at 760mmHg |
| Molecular Formula | C27H46S | Melting Point | 97-99ºC(lit.) |
| MSDS | ChineseUSA | Flash Point | 224ºC |
Names
| Name | Cholest-5-ene-3.β.-thiol |
|---|---|
| Synonym | More Synonyms |
Cholest-5-ene-3-thiol,(3b)- BiologicalActivity
| Description | Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| References | [1]. Huang Z, et al. Thiocholesterol-based lipids for ordered assembly of bioresponsive gene carriers. Mol Ther. 2005 Mar;11(3):409-17. [2]. Ya. A. Gromova, et al. Adsorption Properties of Hybrid Metal–Mesogenic Silver–Cholesterol and Silver–Thiocholesterol Nanosystems. PHYSICAL CHEMISTRY OF NANOCLUSTERS AND NANOMATERIALS. 2019. |
Chemical & Physical Properties
| Density | 0.98g/cm3 |
|---|---|
| Boiling Point | 482.4ºC at 760mmHg |
| Melting Point | 97-99ºC(lit.) |
| Molecular Formula | C27H46S |
| Molecular Weight | 402.71900 |
| Flash Point | 224ºC |
| Exact Mass | 402.33200 |
| PSA | 38.80000 |
| LogP | 8.32620 |
| Vapour Pressure | 5.38E-09mmHg at 25°C |
| Index of Refraction | 1.53 |
| InChIKey | QGVQZRDQPDLHHV-DPAQBDIFSA-N |
| SMILES | CC(C)CCCC(C)C1CCC2C3CC=C4CC(S)CCC4(C)C3CCC12C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles13
More Articles| The hedgehog receptor patched is involved in cholesterol transport. PLoS ONE 6 , e23834, (2011) Sonic hedgehog (Shh) signaling plays a crucial role in growth and patterning during embryonic development, and also in stem cell maintenance and tissue regeneration in adults. Aberrant Shh pathway act... | |
| Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles. Biomacromolecules 9(10) , 2693-704, (2008) Poly(amidoamine) (PAA) networks that are obtained by the use of cystamine as a cross-linking agent in the reaction with 2,2'-dithiodipyridine turn into linear PAAs with dithiopyridyl side groups that ... | |
| Effect of the nature of the spacer on gene transfer efficacies of novel thiocholesterol derived gemini lipids in different cell lines: a structure-activity investigation. J. Med. Chem. 51(8) , 2533-40, (2008) A structure-activity investigation was undertaken to see the effect of the nature of the spacer on the gene transfection efficacies of thiocholesterol-derived cationic gemini lipids possessing disulfi... |
Synonyms
| EINECS 215-003-4 |
| Cholest-5-ene-3b-thiol |
| 3-thiocholesterol |
| MFCD00003647 |
| 5-CHOLESTEN-3ALPHA-THIOL |
| THIOCHOLESTEROL SEALED AMPULE |
| THIOCHOLESTEROL |
| Cholesteryl mercaptan |
| cholest-5-ene-3beta-thiol |
