CAS 661464-94-4|Levalbuterol tartrate

Introduction:Basic information about CAS 661464-94-4|Levalbuterol tartrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameLevalbuterol tartrate
CAS Number661464-94-4Molecular Weight628.71
Density/Boiling Point/
Molecular FormulaC30H48N2O12Melting Point/
MSDS/Flash Point/

Names

Name4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol,(2R,3R)-2,3-dihydroxybutanedioic acid
SynonymMore Synonyms

Levalbuterol tartrate BiologicalActivity

DescriptionLevosalbutamol tartrate(levalbuterol) is the R-enantiomer of the short-acting β2-adrenergic receptor agonist salbutamol. IC50 Value:Target: β2-adrenergic receptorLevosalbutamol and salbutamol produced significantly better bronchodilator responses than placebo. Both the drugs showed equivalent time-dependent bronchodilator responses as measured by area under curve for percent change in FEV(1) and FVC over 6h. The time to onset of action, mean maximum bronchodilator response and duration of bronchodilator response were similar between levosalbutamol and salbutamol [1].
Related CatalogSignaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Neurological Disease
References

[1]. Jantikar A, et al. Comparison of bronchodilator responses of levosalbutamol and salbutamol given via a pressurized metered dose inhaler: a randomized, double blind, single-dose, crossover study. Respir Med. 2007 Apr;101(4):845-9.

Chemical & Physical Properties

Molecular FormulaC30H48N2O12
Molecular Weight628.71
PSA187.78000
Storage condition2-8℃

Synonyms

Levalbuterol tartrate
Xopenex HFA
(2R,3R)-2,3-Dihydroxysuccinic acid - 2-(hydroxymethyl)-4-{(1R)-1-hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}phenol (1:2)
Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-, compd. with (αR)-α-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol (1:2)
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