Introduction:Basic information about CAS 661464-94-4|Levalbuterol tartrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Levalbuterol tartrate |
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| CAS Number | 661464-94-4 | Molecular Weight | 628.71 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C30H48N2O12 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol,(2R,3R)-2,3-dihydroxybutanedioic acid |
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| Synonym | More Synonyms |
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Levalbuterol tartrate BiologicalActivity
| Description | Levosalbutamol tartrate(levalbuterol) is the R-enantiomer of the short-acting β2-adrenergic receptor agonist salbutamol. IC50 Value:Target: β2-adrenergic receptorLevosalbutamol and salbutamol produced significantly better bronchodilator responses than placebo. Both the drugs showed equivalent time-dependent bronchodilator responses as measured by area under curve for percent change in FEV(1) and FVC over 6h. The time to onset of action, mean maximum bronchodilator response and duration of bronchodilator response were similar between levosalbutamol and salbutamol [1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Neurological Disease |
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| References | [1]. Jantikar A, et al. Comparison of bronchodilator responses of levosalbutamol and salbutamol given via a pressurized metered dose inhaler: a randomized, double blind, single-dose, crossover study. Respir Med. 2007 Apr;101(4):845-9. |
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Chemical & Physical Properties
| Molecular Formula | C30H48N2O12 |
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| Molecular Weight | 628.71 |
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| PSA | 187.78000 |
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| Storage condition | 2-8℃ |
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Synonyms
| Levalbuterol tartrate |
| Xopenex HFA |
| (2R,3R)-2,3-Dihydroxysuccinic acid - 2-(hydroxymethyl)-4-{(1R)-1-hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}phenol (1:2) |
| Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-, compd. with (αR)-α-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol (1:2) |