Introduction:Basic information about CAS 80665-72-1|Fuziline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fuziline |
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| CAS Number | 80665-72-1 | Molecular Weight | 453.569 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 596.9±50.0 °C at 760 mmHg |
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| Molecular Formula | C24H39NO7 | Melting Point | 206-207ºC |
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| MSDS | / | Flash Point | 314.8±30.1 °C |
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Names
| Name | 15-α-hydroxyneoline |
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| Synonym | More Synonyms |
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Fuziline BiologicalActivity
| Description | Fuziline is a alkaloid isolated from the lateral roots of Aconitum carmichaelii[1]. |
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| Related Catalog | Signaling Pathways >>Others >>Others |
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| In Vitro | Fuziline shows activity against pentobarbital sodiuminduced cardiomyocytes damage by obviously recovering beating rhythm and increasing the cell viability[1]. |
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| In Vivo | Fuziline exhibits the mean half-life of 5.93 hours, 6.13 hours and 5.12 hours for 14 mg/kg, 2 4 mg/kg and 4 mg/kg, respectively, by oral administration in rat[2]. |
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| References | [1]. Xiong L, et al. Alkaloids isolated from the lateral root of Aconitum carmichaelii. Molecules. 2012 Aug 20;17(8):9939-46. [2]. Li YX, et al. Development and validation of a UHPLC-qTOF-MS method for quantification of fuziline in rat plasma and its application in a pharmacokinetic study. Biomed Chromatogr. 2014 Dec;28(12):1707-13. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 596.9±50.0 °C at 760 mmHg |
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| Melting Point | 206-207ºC |
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| Molecular Formula | C24H39NO7 |
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| Molecular Weight | 453.569 |
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| Flash Point | 314.8±30.1 °C |
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| Exact Mass | 453.272644 |
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| PSA | 111.85000 |
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| LogP | -1.32 |
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| Vapour Pressure | 0.0±3.8 mmHg at 25°C |
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| Index of Refraction | 1.617 |
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| InChIKey | FPECZWKKKKZPPP-PVALPMDTSA-N |
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| SMILES | CCN1CC2(COC)CCC(O)C34C5CC6C(O)C5C(O)(C(O)C6OC)C(C(OC)C23)C14 |
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| Storage condition | 2-8C |
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Synonyms
| (1α,6α,10α,13ξ,14α,15α,16β,17ξ)-20-Ethyl-6,16-dimethoxy-4-(methoxymethyl)aconitane-1,8,14,15-tetrol |
| senbusine-C |
| Aconitane-1,8,14,15-tetrol,20-ethyl-6,16-dimethoxy-4-(methoxymethyl)-,(1alpha,6alpha,14alpha,15alpha,16beta) |
| Aconitane-1,8,14,15-tetrol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)-, (1α,6α,10α,13ξ,14α,15α,16β,17ξ)- |