CAS 503559-84-0|glucagon receptor antagonists-1

Introduction:Basic information about CAS 503559-84-0|glucagon receptor antagonists-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Nameglucagon receptor antagonists-1
CAS Number503559-84-0Molecular Weight447.58400
Density1.094Boiling Point/
Molecular FormulaC29H34FNO2Melting Point/
MSDS/Flash Point/

Names

Name4-[4-Fluoro-2-(phenylmethoxy)phenyl]-α-methyl-2,6-bis(1-methylethyl)-5-(1-propen-1-yl)-3-Pyridinemethanol
SynonymMore Synonyms

glucagon receptor antagonists-1 BiologicalActivity

DescriptionGlucagon receptor antagonists-1 is a highly potent glucagon receptor antagonist.
Related CatalogSignaling Pathways >>GPCR/G Protein >>Glucagon ReceptorResearch Areas >>Metabolic Disease
References

[1]. Ladouceur, Gaetan H. et al. Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists. Bioorganic & Medicinal Chemistry Letters (2002), 12(23), 3421-3424.

Chemical & Physical Properties

Density1.094
Molecular FormulaC29H34FNO2
Molecular Weight447.58400
Exact Mass447.25700
PSA42.35000
LogP7.79990
InChIKeyHERVQUFQZXZOBU-YRNVUSSQSA-N
SMILESCC=Cc1c(C(C)C)nc(C(C)C)c(C(C)O)c1-c1ccc(F)cc1OCc1ccccc1
Storage condition2-8℃

Synonyms

1-(4-(2-(Benzyloxy)-4-fluorophenyl)-2,6-diisopropyl-5-(prop-1-en-1-yl)pyridin-3-yl)ethanol
4-[4-Fluoro-2-(phenylmethoxy)phenyl]-alpha-methyl-2,6-bis(1-methylethyl)-5-(1-propen-1-yl)-3-pyridinemethanol
glucagon receptor antagonists 1
glucagon receptor antagonists-1
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